From Wikipedia, the free encyclopedia
The
glucocorticoid receptor .
The corticosteroid receptors are
receptors for
corticosteroids .
[1] They include the following two
nuclear receptors :
[1]
[2]
[3]
There are also
membrane corticosteroid receptors , including the
membrane glucocorticoid receptors and the
membrane mineralocorticoid receptors , which are not well-characterized at present.
[4]
[5]
[6]
References
^
a
b Scott T. Brady; George J. Siegel; Robert Wayne Albers; Donald Lowell Price (2012).
Basic Neurochemistry: Principles of Molecular, Cellular and Medical Neurobiology . Academic Press. pp. 522–.
ISBN
978-0-12-374947-5 .
^ Eugenia Wang; D. Stephen Snyder (13 August 1998).
Handbook of the Aging Brain . Academic Press. pp. 22–.
ISBN
978-0-08-053322-3 .
^
Hormones, Brain and Behavior, Five-Volume Set . Academic Press. 18 June 2002. pp. 267–.
ISBN
978-0-08-053415-2 .
^ Groeneweg FL, Karst H, de Kloet ER, Joëls M (2012). "Mineralocorticoid and glucocorticoid receptors at the neuronal membrane, regulators of nongenomic corticosteroid signalling". Mol. Cell. Endocrinol . 350 (2): 299–309.
doi :
10.1016/j.mce.2011.06.020 .
PMID
21736918 .
S2CID
23048944 .
^ Tasker JG, Di S, Malcher-Lopes R (2006).
"Minireview: rapid glucocorticoid signaling via membrane-associated receptors" . Endocrinology . 147 (12): 5549–56.
doi :
10.1210/en.2006-0981 .
PMC
3280589 .
PMID
16946006 .
^ Dooley R, Harvey BJ, Thomas W (2012).
"Non-genomic actions of aldosterone: from receptors and signals to membrane targets" . Mol. Cell. Endocrinol . 350 (2): 223–34.
doi :
10.1016/j.mce.2011.07.019 .
PMID
21801805 .
S2CID
24630510 .
(1) Basic domains
(1.1) Basic
leucine zipper (
bZIP )(1.2) Basic helix-loop-helix (
bHLH )
Group A Group B Group C bHLH-
PAS Group D Group E Group F bHLH-COE
(1.3)
bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2)
Zinc finger DNA-binding domains
(2.1)
Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors
GR Tooltip Glucocorticoid receptor
MR Tooltip Mineralocorticoid receptor