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Routes of administration | By mouth |
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Formula | C24H34O3S |
Molar mass | 402.59 g·mol−1 |
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Spiroxasone ( INN , USAN ) is a synthetic, steroidal antimineralocorticoid of the spirolactone group which was developed as a diuretic and antihypertensive agent but was never marketed. [1] [2] It was synthesized and assayed in 1963. [1] The drug is 7α-acetylthiospirolactone with the ketone group removed from the C17α spirolactone ring. [1] Similarly to other spirolactones like spironolactone, spiroxasone also possesses antiandrogen activity. [3] [4]
Spiroxasone [...] is also an anti-androgen [379].