From Wikipedia, the free encyclopedia
Family of proteins
Consisting of about 110
amino acids, the domain in winged-helix transcription factors (see
Regulation of gene expression) has four helices and a two-strand
beta-sheet.
These proteins are classified into 19 families called FoxA-FoxS.
Mutations in FoxP proteins are implicated in human
autoimmune diseases.
See also
External links
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(1) Basic domains |
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(1.1) Basic
leucine zipper (
bZIP) | |
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(1.2) Basic helix-loop-helix (
bHLH) | Group A | |
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Group B | |
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Group C bHLH-
PAS | |
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Group D | |
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Group E | |
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Group F bHLH-COE | |
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(1.3)
bHLH-ZIP | |
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(1.4) NF-1 | |
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(1.5) RF-X | |
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(1.6) Basic helix-span-helix (bHSH) | |
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(2)
Zinc finger DNA-binding domains |
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(2.1)
Nuclear receptor (Cys4) | subfamily 1 | |
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subfamily 2 | |
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subfamily 3 | |
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subfamily 4 | |
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subfamily 5 | |
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subfamily 6 | |
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subfamily 0 | |
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(2.2) Other Cys4 | |
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(2.3) Cys2His2 | |
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(2.4) Cys6 | |
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(2.5) Alternating composition | |
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(2.6) WRKY | |
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(4) β-Scaffold factors with minor groove contacts |
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(0) Other transcription factors |
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