From Wikipedia, the free encyclopedia
Chemical compound
Cortivazol
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International Drug Names |
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ATC code | |
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(11β,16α)-21-(Acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-2'H-pregna-2,4,6-trieno[3,2-c]pyrazol-20-one
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CompTox Dashboard (
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ECHA InfoCard |
100.012.887
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Formula | C32H38N2O5 |
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Molar mass | 530.665 g·mol−1 |
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3D model (
JSmol) | |
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O=C(OCC(=O)[C@@]4(O)[C@H](C)C[C@H]5[C@@H]6/C=C(\C3=C\c1c(cnn1c2ccccc2)C[C@@]3([C@H]6[C@@H](O)C[C@]45C)C)C)C
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InChI=1S/C32H38N2O5/c1-18-11-23-25-12-19(2)32(38,28(37)17-39-20(3)35)31(25,5)15-27(36)29(23)30(4)14-21-16-33-34(26(21)13-24(18)30)22-9-7-6-8-10-22/h6-11,13,16,19,23,25,27,29,36,38H,12,14-15,17H2,1-5H3/t19-,23+,25+,27+,29-,30+,31+,32+/m1/s1 YKey:RKHQGWMMUURILY-UHRZLXHJSA-N Y
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NY
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Cortivazol is a high-affinity
agonist
ligand for the
glucocorticoid receptor and consequently is classified as a
glucocorticoid.
[1]
It is sometimes abbreviated "CVZ".
[2]
References
External links
Cortivazol at the U.S. National Library of Medicine
Medical Subject Headings (MeSH)
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GRTooltip Glucocorticoid receptor | |
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