From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
POU domain, class 3, transcription factor 1 (also known as Oct-6 ) is a
protein that in humans is encoded by the POU3F1
gene .
[3]
[4]
See also
References
Further reading
Monuki ES, Kuhn R, Weinmaster G, Trapp BD, Lemke G (Sep 1990). "Expression and activity of the POU transcription factor SCIP". Science . 249 (4974): 1300–3.
Bibcode :
1990Sci...249.1300M .
doi :
10.1126/science.1975954 .
PMID
1975954 .
Suzuki N, Rohdewohld H, Neuman T, Gruss P, Schöler HR (Nov 1990).
"Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain" . The EMBO Journal . 9 (11): 3723–32.
doi :
10.1002/j.1460-2075.1990.tb07585.x .
PMC
552128 .
PMID
1976514 .
Zwilling S, König H, Wirth T (Mar 1995).
"High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors" . The EMBO Journal . 14 (6): 1198–208.
doi :
10.1002/j.1460-2075.1995.tb07103.x .
PMC
398197 .
PMID
7720710 .
Leger H, Sock E, Renner K, Grummt F, Wegner M (Jul 1995).
"Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y" . Molecular and Cellular Biology . 15 (7): 3738–47.
doi :
10.1128/mcb.15.7.3738 .
PMC
230612 .
PMID
7791781 .
Faus I, Hsu HJ, Fuchs E (May 1994).
"Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia" . Molecular and Cellular Biology . 14 (5): 3263–75.
doi :
10.1128/mcb.14.5.3263 .
PMC
358693 .
PMID
7909356 .
Abdel-Rahman B, Fiddler M, Rappolee D, Pergament E (Oct 1995). "Expression of transcription regulating genes in human preimplantation embryos". Human Reproduction . 10 (10): 2787–92.
doi :
10.1093/oxfordjournals.humrep.a135792 .
PMID
8567814 .
Jaegle M, Mandemakers W, Broos L, Zwart R, Karis A, Visser P, Grosveld F, Meijer D (Jul 1996). "The POU factor Oct-6 and Schwann cell differentiation". Science . 273 (5274): 507–10.
Bibcode :
1996Sci...273..507J .
doi :
10.1126/science.273.5274.507 .
PMID
8662541 .
S2CID
39349653 .
Sock E, Enderich J, Rosenfeld MG, Wegner M (Jul 1996).
"Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6" . The Journal of Biological Chemistry . 271 (29): 17512–8.
doi :
10.1074/jbc.271.29.17512 .
PMID
8663425 .
Malik KF, Jaffe H, Brady J, Young WS (Apr 1997).
"The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U" . Brain Research. Molecular Brain Research . 45 (1): 99–107.
doi :
10.1016/S0169-328X(96)00238-0 .
PMID
9105675 .
Sumiyama K, Washio-Watanabe K, Ono T, Yoshida MC, Hayakawa T, Ueda S (Feb 1998). "Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2". Mammalian Genome . 9 (2): 180–1.
doi :
10.1007/s003359900721 .
PMID
9457692 .
S2CID
9495282 .
Arroyo EJ, Bermingham JR, Rosenfeld MG, Scherer SS (Oct 1998).
"Promyelinating Schwann cells express Tst-1/SCIP/Oct-6" . The Journal of Neuroscience . 18 (19): 7891–902.
doi :
10.1523/JNEUROSCI.18-19-07891.1998 .
PMC
6792991 .
PMID
9742157 .
Kawasaki T, Oka N, Tachibana H, Akiguchi I, Shibasaki H (Mar 2003). "Oct6, a transcription factor controlling myelination, is a marker for active nerve regeneration in peripheral neuropathies". Acta Neuropathologica . 105 (3): 203–8.
doi :
10.1007/s00401-002-0630-9 .
hdl :
2433/148771 .
PMID
12557005 .
S2CID
2340303 .
Beck IM, Müller M, Mentlein R, Sadowski T, Mueller MS, Paus R, Sedlacek R (May 2007).
"Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation" . The Journal of Investigative Dermatology . 127 (5): 1107–14.
doi :
10.1038/sj.jid.5700674 .
PMID
17195013 .
Ryu EJ, Wang JY, Le N, Baloh RH, Gustin JA, Schmidt RE, Milbrandt J (Oct 2007).
"Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss" . The Journal of Neuroscience . 27 (43): 11552–9.
doi :
10.1523/JNEUROSCI.5497-06.2007 .
PMC
6673231 .
PMID
17959798 .
External links
This article incorporates text from the
United States National Library of Medicine , which is in the
public domain .
(1) Basic domains
(1.1) Basic
leucine zipper (
bZIP )(1.2) Basic helix-loop-helix (
bHLH )
Group A Group B Group C bHLH-
PAS Group D Group E Group F bHLH-COE
(1.3)
bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2)
Zinc finger DNA-binding domains
(2.1)
Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors