From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Nuclear factor 1 C-type is a
protein that in humans is encoded by the NFIC
gene .
[5]
[6]
[7]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000141905 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000055053 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Santoro C, Mermod N, Andrews PC, Tjian R (Aug 1988). "A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs". Nature . 334 (6179): 218–24.
Bibcode :
1988Natur.334..218S .
doi :
10.1038/334218a0 .
PMID
3398920 .
S2CID
4287831 .
^ Qian F, Kruse U, Lichter P, Sippel AE (Dec 1995). "Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH". Genomics . 28 (1): 66–73.
doi :
10.1006/geno.1995.1107 .
PMID
7590749 .
^
"Entrez Gene: NFIC nuclear factor I/C (CCAAT-binding transcription factor)" .
Further reading
Blau J, Xiao H, McCracken S, et al. (1996).
"Three functional classes of transcriptional activation domain" . Mol. Cell. Biol . 16 (5): 2044–55.
doi :
10.1128/MCB.16.5.2044 .
PMC
231191 .
PMID
8628270 .
Wenzelides S, Altmann H, Wendler W, Winnacker EL (1996).
"CTF5--a new transcriptional activator of the NFI/CTF family" . Nucleic Acids Res . 24 (12): 2416–21.
doi :
10.1093/nar/24.12.2416 .
PMC
145930 .
PMID
8710515 .
Liu Y, Bernard HU, Apt D (1997).
"NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing" . J. Biol. Chem . 272 (16): 10739–45.
doi :
10.1074/jbc.272.16.10739 .
PMID
9099724 .
Nogues G, Kadener S, Cramer P, et al. (2003).
"Transcriptional activators differ in their abilities to control alternative splicing" . J. Biol. Chem . 277 (45): 43110–4.
doi :
10.1074/jbc.M208418200 .
PMID
12221105 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Norquay LD, Yang X, Sheppard P, et al. (2003). "RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin". Mol. Endocrinol . 17 (6): 1027–38.
doi :
10.1210/me.2003-0025 .
PMID
12624117 .
Wickenheisser JK, Nelson-DeGrave VL, Quinn PG, McAllister JM (2004).
"Increased cytochrome P450 17alpha-hydroxylase promoter function in theca cells isolated from patients with polycystic ovary syndrome involves nuclear factor-1" . Mol. Endocrinol . 18 (3): 588–605.
doi :
10.1210/me.2003-0090 .
PMID
14684846 .
Grimwood J, Gordon LA, Olsen A, et al. (2004).
"The DNA sequence and biology of human chromosome 19" . Nature . 428 (6982): 529–35.
Bibcode :
2004Natur.428..529G .
doi :
10.1038/nature02399 .
PMID
15057824 .
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004).
"Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proc. Natl. Acad. Sci. U.S.A . 101 (33): 12130–5.
Bibcode :
2004PNAS..10112130B .
doi :
10.1073/pnas.0404720101 .
PMC
514446 .
PMID
15302935 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Zhao LH, Ba XQ, Wang XG, et al. (2005).
"BAF complex is closely related to and interacts with NF1/CTF and RNA polymerase II in gene transcriptional activation" . Acta Biochim. Biophys. Sin. (Shanghai) . 37 (7): 440–6.
doi :
10.1111/j.1745-7270.2005.00061.x .
PMID
15999204 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8.
Bibcode :
2005Natur.437.1173R .
doi :
10.1038/nature04209 .
PMID
16189514 .
S2CID
4427026 .
Nilsson J, Bjursell G, Kannius-Janson M (2006).
"Nuclear Jak2 and transcription factor NF1-C2: a novel mechanism of prolactin signaling in mammary epithelial cells" . Mol. Cell. Biol . 26 (15): 5663–74.
doi :
10.1128/MCB.02095-05 .
PMC
1592781 .
PMID
16847321 .
Olsen JV, Blagoev B, Gnad F, et al. (2006).
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48.
doi :
10.1016/j.cell.2006.09.026 .
PMID
17081983 .
S2CID
7827573 .
Hebbar PB, Archer TK (2007).
"Chromatin-dependent cooperativity between site-specific transcription factors in vivo" . J. Biol. Chem . 282 (11): 8284–91.
doi :
10.1074/jbc.M610554200 .
PMC
2528297 .
PMID
17186943 .
External links
This article incorporates text from the
United States National Library of Medicine , which is in the
public domain .
(1) Basic domains
(1.1) Basic
leucine zipper (
bZIP )(1.2) Basic helix-loop-helix (
bHLH )
Group A Group B Group C bHLH-
PAS Group D Group E Group F bHLH-COE
(1.3)
bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2)
Zinc finger DNA-binding domains
(2.1)
Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors