Homeobox A4, also known as HOXA4, is a
protein which in humans is encoded by the HOXA4gene.[5][6]
Function
In vertebrates, the genes encoding the class of
transcription factors called
homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes.[7] Expression of these proteins is spatially and temporally regulated during
embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate
gene expression,
morphogenesis, and
differentiation.[5]
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doi:
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doi:
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PMID7654365.
S2CID43123886.
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doi:
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PMID8646877.
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doi:
10.1007/BF02072541.
PMID8688592.
S2CID28126784.
Duluc I, Lorentz O, Fritsch C, et al. (1997). "Changing intestinal connective tissue interactions alters homeobox gene expression in epithelial cells". J. Cell Sci. 110 (11): 1317–24.
doi:
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PMID9202392.
Kosaki K, Kosaki R, Suzuki T, et al. (2002). "Complete mutation analysis panel of the 39 human HOX genes". Teratology. 65 (2): 50–62.
doi:
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PMID11857506.
Larramendy ML, Niini T, Elonen E, et al. (2003). "Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis". Haematologica. 87 (6): 569–77.
PMID12031912.
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PMID12520199.