Bone morphogenetic protein type I receptors are single pass, type I transmembrane proteins. They belong to a class of receptor serine/threonine kinases that bind members of the TGF beta superfamily of ligands—the bone morphogenetic proteins.
The three types of type I BMP receptors are ACVR1, BMPR1A and BMPR1B.
TGF beta superfamily of ligands |
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TGF beta receptors ( Activin, BMP, family) |
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Transducers/ SMAD | |||||||
Ligand inhibitors | |||||||
Coreceptors | |||||||
Other |
Type I cytokine receptor | |||||||||||||
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Receptor protein serine/threonine kinase | |||||||||||||
Receptor tyrosine kinase |
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Tumor necrosis factor receptor | |||||||||||||
Ig superfamily | |||||||||||||
Other/ungrouped |
Activity | |
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Regulation | |
Classification | |
Kinetics | |
Types |
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