From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Kinase suppressor of Ras 1 is an
enzyme that in humans is encoded by the KSR1
gene.
[5]
[6]
References
- ^
a
b
c
GRCh38: Ensembl release 89: ENSG00000141068 –
Ensembl, May 2017
- ^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000018334 –
Ensembl, May 2017
-
^
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
-
^
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
-
^ Therrien M, Chang HC, Solomon NM, Karim FD, Wassarman DA, Rubin GM (Jan 1996).
"KSR, a novel protein kinase required for RAS signal transduction". Cell. 83 (6): 879–88.
doi:
10.1016/0092-8674(95)90204-X.
PMID
8521512.
S2CID
16975824.
-
^
"Entrez Gene: KSR1 kinase suppressor of ras 1".
Further reading
- Goettel JA, Liang D, Hilliard VC, et al. (2011).
"KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1". Exp. Cell Res. 317 (4): 452–63.
doi:
10.1016/j.yexcr.2010.11.018.
PMC
3038243.
PMID
21144847.
- Kolesnick R, Xing HR (2004).
"Inflammatory bowel disease reveals the kinase activity of KSR1". J. Clin. Invest. 114 (9): 1233–7.
doi:
10.1172/JCI23441.
PMC
524240.
PMID
15520853.
- Xing HR, Lozano J, Kolesnick R (2000).
"Epidermal growth factor treatment enhances the kinase activity of kinase suppressor of Ras". J. Biol. Chem. 275 (23): 17276–80.
doi:
10.1074/jbc.C900989199.
PMID
10764733.
- Roy F, Therrien M (2002).
"MAP kinase module: the Ksr connection". Curr. Biol. 12 (9): R325–7.
Bibcode:
2002CBio...12.R325R.
doi:
10.1016/S0960-9822(02)00831-X.
PMID
12007434.
S2CID
17763459.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.
Bibcode:
2002PNAS...9916899M.
doi:
10.1073/pnas.242603899.
PMC
139241.
PMID
12477932.
- Matheny SA, Chen C, Kortum RL, et al. (2004). "Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP". Nature. 427 (6971): 256–60.
Bibcode:
2004Natur.427..256M.
doi:
10.1038/nature02237.
PMID
14724641.
S2CID
4416552.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7.
doi:
10.1101/gr.2596504.
PMC
528928.
PMID
15489334.
- Kim M, Yan Y, Kortum RL, et al. (2005).
"Expression of kinase suppressor of Ras1 enhances cisplatin-induced extracellular signal-regulated kinase activation and cisplatin sensitivity". Cancer Res. 65 (10): 3986–92.
doi:
10.1158/0008-5472.CAN-03-2334.
PMID
15899786.
- Zody MC, Garber M, Adams DJ, et al. (2006).
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage". Nature. 440 (7087): 1045–9.
Bibcode:
2006Natur.440.1045Z.
doi:
10.1038/nature04689.
PMC
2610434.
PMID
16625196.
- Wang X, Wang TT, White JH, Studzinski GP (2006).
"Induction of kinase suppressor of RAS-1(KSR-1) gene by1, α25-dihydroxyvitamin D3 in human leukemia HL60 cells through a vitamin D response element in the 5′-flanking region". Oncogene. 25 (53): 7078–85.
doi:
10.1038/sj.onc.1209697.
PMC
2843694.
PMID
16732322.
- Olsen JV, Blagoev B, Gnad F, et al. (2006).
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48.
doi:
10.1016/j.cell.2006.09.026.
PMID
17081983.
S2CID
7827573.
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