Thiamin pyrophosphokinase 1 is an
enzyme that in humans is encoded by the TPK1gene.[5][6]
This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of
thiamine to thiamine pyrophosphate. Alternate transcriptional
splice variants, encoding different isoforms, have been characterized.[6]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Nosaka K, Onozuka M, Kakazu N, Hibi S, Nishimura H, Nishino H, Abe T (May 2001). "Isolation and characterization of a human thiamine pyrophosphokinase cDNA". Biochim Biophys Acta. 1517 (2): 293–7.
doi:
10.1016/s0167-4781(00)00247-5.
PMID11342111.
Egi Y, Koyama S, Shioda T, et al. (1992). "Identification, purification and reconstitution of thiamin metabolizing enzymes in human red blood cells". Biochim. Biophys. Acta. 1160 (2): 171–8.
doi:
10.1016/0167-4838(92)90004-W.
PMID1332781.
Bohn H, Winckler W (1985). "Isolation and characterization of four new placental tissue proteins (PP18, PP19, PP20, PP21)". Arch. Gynecol. 236 (4): 235–42.
doi:
10.1007/BF02133941.
PMID3896163.
S2CID6395375.
Iwashima A, Kinugasa A, Nose Y (1983). "Radiometric assay for thiamine pyrophosphokinase activity in human leukocytes". Acta Vitaminol. Enzymol. 5 (1): 41–5.
PMID6303095.