Serine/threonine-protein kinase Sgk2 is an
enzyme that in humans is encoded by the SGK2gene.[5][6]
This gene encodes a
serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (
SGK), this gene is not induced by
serum or
glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase (
PI3K), which is also true for SGK. Two
alternate transcripts encoding two different
isoforms have been described.[6]
Gamper N, Fillon S, Feng Y, et al. (2003). "K+ channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK". Pflügers Arch. 445 (1): 60–6.
doi:
10.1007/s00424-002-0873-2.
PMID12397388.
S2CID21073737.
Friedrich B, Feng Y, Cohen P, et al. (2003). "The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC". Pflügers Arch. 445 (6): 693–6.
doi:
10.1007/s00424-002-0993-8.
PMID12632189.
S2CID32511608.
Embark HM, Böhmer C, Vallon V, et al. (2003). "Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms". Pflügers Arch. 445 (5): 601–6.
doi:
10.1007/s00424-002-0982-y.
PMID12634932.
S2CID22981271.