From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
PAS domain-containing serine/threonine-protein kinase is an
enzyme that in humans is encoded by the PASK
gene .
[5]
[6]
[7]
[8]
PAS domains regulate the function of many
intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. PASK is an evolutionarily conserved protein present in
yeast ,
flies , and
mammals .[supplied by OMIM]
[8]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000115687 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000026274 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Hofer T, Spielmann P, Stengel P, Stier B, Katschinski DM, Desbaillets I, Gassmann M, Wenger RH (Nov 2001).
"Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors" (PDF) . Biochem Biophys Res Commun . 288 (4): 757–64.
doi :
10.1006/bbrc.2001.5840 .
PMID
11688972 . Archived from
the original (PDF) on 2013-11-02. Retrieved 2018-12-22 .
^ Rutter J, Michnoff CH, Harper SM, Gardner KH, McKnight SL (Aug 2001).
"PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase" . Proc Natl Acad Sci U S A . 98 (16): 8991–6.
Bibcode :
2001PNAS...98.8991R .
doi :
10.1073/pnas.161284798 .
PMC
55361 .
PMID
11459942 .
^ da Silva Xavier G, Rutter J, Rutter GA (Jun 2004).
"Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose" . Proc Natl Acad Sci U S A . 101 (22): 8319–24.
Bibcode :
2004PNAS..101.8319D .
doi :
10.1073/pnas.0307737101 .
PMC
420392 .
PMID
15148392 .
^
a
b
"Entrez Gene: PASK PAS domain containing serine/threonine kinase" .
Further reading
Nakajima D, Okazaki N, Yamakawa H, et al. (2003).
"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones" (PDF) . DNA Res . 9 (3): 99–106.
doi :
10.1093/dnares/9.3.99 .
PMID
12168954 .
Nagase T, Seki N, Tanaka A, et al. (1996).
"Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1" . DNA Res . 2 (4): 167–74, 199–210.
doi :
10.1093/dnares/2.4.167 .
PMID
8590280 .
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem . 236 (1): 107–13.
doi :
10.1006/abio.1996.0138 .
PMID
8619474 .
Yu W, Andersson B, Worley KC, et al. (1997).
"Large-scale concatenation cDNA sequencing" . Genome Res . 7 (4): 353–8.
doi :
10.1101/gr.7.4.353 .
PMC
139146 .
PMID
9110174 .
Ceulemans H, Van Eynde A, Pérez-Callejón E, et al. (1999).
"Structure and splice products of the human gene encoding sds22, a putative mitotic regulator of protein phosphatase-1" . Eur. J. Biochem . 262 (1): 36–42.
doi :
10.1046/j.1432-1327.1999.00344.x .
PMID
10231361 .
Amezcua CA, Harper SM, Rutter J, Gardner KH (2003).
"Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation" . Structure . 10 (10): 1349–61.
doi :
10.1016/S0969-2126(02)00857-2 .
PMID
12377121 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004).
"Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proc. Natl. Acad. Sci. U.S.A . 101 (33): 12130–5.
Bibcode :
2004PNAS..10112130B .
doi :
10.1073/pnas.0404720101 .
PMC
514446 .
PMID
15302935 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Ewing RM, Chu P, Elisma F, et al. (2007).
"Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .
Eckhardt K, Troger J, Reissmann J, et al. (2007).
"Male germ cell expression of the PAS domain kinase PASKIN and its novel target eukaryotic translation elongation factor eEF1A1" . Cell. Physiol. Biochem . 20 (1–4): 227–40.
doi :
10.1159/000104169 .
PMID
17595531 .
Kikani CK, Antonysamy SA, Bonanno JB, et al. (2010).
"Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation" . J. Biol. Chem . 285 (52): 41034–43.
doi :
10.1074/jbc.M110.157594 .
PMC
3003402 .
PMID
20943661 .
Activity Regulation Classification Kinetics Types