From Wikipedia, the free encyclopedia
Class of enzymes
| Receptor protein serine/threonine kinase |
|---|
|
| Symbol | Receptor protein serine/threonine kinase |
|---|
|
Membranome |
3 |
|---|
Receptor protein serine/threonine kinases (
EC
2.7.11.30) are
enzyme-linked receptors that belong to
protein-serine/threonine kinases. The
systematic name of this enzyme class is ATP:[receptor-protein] phosphotransferase. Proteins from this group participate in 7
metabolic pathways:
MAPK signaling pathway,
cytokine-cytokine receptor interaction,
TGF beta signaling pathway,
adherens junction,
colorectal cancer,
pancreatic cancer, and
chronic myeloid leukemia.
Links
References
- Wrana JL, Attisano L, Wieser R, Ventura F, Massague J (1994). "Mechanism of activation of the TGF-beta receptor". Nature. 370 (6488): 341–7.
Bibcode:
1994Natur.370..341W.
doi:
10.1038/370341a0.
PMID
8047140.
S2CID
4344481.
- Massague J, Chen YG (2000). "Controlling TGF-beta signaling". Genes Dev. 14 (6): 627–44.
PMID
10733523.
- Lechleider RJ; Hemmati, P; Larisch-Bloch, S; Ajmera, R; Roberts, AB; Lechleider, RJ (1997).
"Characterization of functional domains within Smad4/DPC4". J. Biol. Chem. 272 (21): 13690–6.
doi:
10.1074/jbc.272.21.13690.
PMID
9153220.
