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Chemical compound
Reposal
Other names Reposamal, 5-Ethyl-5-(bicyclo(3.2.1)octenyl)barbituric acid
ATC code
5-bicyclo[3.2.1]oct-2-en-3-yl-5-ethylpyrimidine-2,4,6(1H ,3H ,5H )-trione
CAS Number
PubChem
CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (
EPA )
Formula C 14 H 18 N 2 O 3
Molar mass 262.309 g·mol−1 3D model (
JSmol )
O=C1NC(=O)NC(=O)C1(CC)C=3C[C@H]2C[C@H](CC2)C=3
InChI=1S/C14H18N2O3/c1-2-14(11(17)15-13(19)16-12(14)18)10-6-8-3-4-9(5-8)7-10/h6,8-9H,2-5,7H2,1H3,(H2,15,16,17,18,19)/t8-,9+/m0/s1
Y Key:MKELYWOVSPVORM-DTWKUNHWSA-N
Y
N Y
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(verify)
Reposal is a
barbiturate derivative invented in the 1960s in Denmark. It has
sedative ,
hypnotic and
anticonvulsant properties, and was used primarily for the treatment of
insomnia .
[1]
[2]
[3]
References
^ Kessing SV, Tarding F, Thomsen AC (December 1963). "Reposal, A New Hypnotic. I. Pharmacodynamic Activity". Ugeskrift for Laeger (in Danish). 125 : 1735–8.
PMID
14103836 .
^ Kessing SV, Tarding F, Thomsen AC (December 1963). "Reposal, A New Hypnotic. Ii. Clinical Effects". Ugeskrift for Laeger (in Danish). 125 : 1739–41.
PMID
14103837 .
^ Nielsen P, Tarding F (1968). "The metabolic fate of 5-(bicyclo-3,2,1,-oct-2-en-2-yl)-5-ethyl barbituric acid, (Reposal)". Acta Pharmacologica et Toxicologica . 26 (6): 521–30.
doi :
10.1111/j.1600-0773.1968.tb00471.x .
PMID
5756387 .
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