As the trade name Tybatran (
Robins), it was formerly available in capsules of 125, 250, and 350 mg, taken 3 or 4 times a day for a total daily dosage of 750 mg to 2 g. The plasma half-life of the drug is three hours. At high doses in combination with
phenothiazines, it could produce convulsions.[3]
^Segelman FH, Kelton E, Terzi RM, Kucharczyk N, Sofia RD (June 1985). "The comparative potency of phenobarbital and five 1,3-propanediol dicarbamates for hepatic cytochrome P450 induction in rats". Research Communications in Chemical Pathology and Pharmacology. 48 (3): 467–70.
PMID4023427.
^American Medical Association Dept of Drugs (1977). AMA Drug Evaluations (3rd ed.). Littleton, Mass.: Pub. Sciences Group. p. 406.
ISBN978-0-88416-175-2.
OCLC1024170745.