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Chemical compound
Iclazepam
7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-3H -1,4-benzodiazepin-2-one
CAS Number
PubChem
CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (
EPA )
Formula C 21 H 21 Cl N 2 O 2
Molar mass 368.86 g·mol−1 3D model (
JSmol )
ClC1=CC2=C(C=C1)N(CCOCC3CC3)C(CN=C2C4=CC=CC=C4)=O
InChI=1S/C21H21ClN2O2/c22-17-8-9-19-18(12-17)21(16-4-2-1-3-5-16)23-13-20(25)24(19)10-11-26-14-15-6-7-15/h1-5,8-9,12,15H,6-7,10-11,13-14H2
Y Key:PLRHQQPBNXIHAZ-UHFFFAOYSA-N
Y
(verify)
Iclazepam (Clazepam ) is a drug which is a
benzodiazepine derivative. It has
sedative and
anxiolytic effects similar to those produced by other benzodiazepine derivatives, and is around the same potency as
chlordiazepoxide .
Iclazepam is a derivative of
nordazepam substituted with a cyclopropylmethoxyethyl group on the N 1 nitrogen. Once in the body, iclazepam is quickly metabolised to
nordazepam and its N -(2-hydroxyethyl) derivative, which are thought to be mainly responsible for its effects.
[1]
See also
References
Alcohols
Barbiturates
Benzodiazepines
Carbamates
Flavonoids
Imidazoles
Kava constituents
Monoureides
Neuroactive steroids
Nonbenzodiazepines
Phenols
Piperidinediones
Pyrazolopyridines
Quinazolinones
Volatiles /
gases Others/unsorted
3-Hydroxybutanal
α-EMTBL
AA-29504
Alogabat
Avermectins (e.g.,
ivermectin )
Bromide compounds (e.g.,
lithium bromide ,
potassium bromide ,
sodium bromide )
Carbamazepine
Chloralose
Chlormezanone
Clomethiazole
Darigabat
DEABL
Deuterated etifoxine
Dihydroergolines (e.g.,
dihydroergocryptine ,
dihydroergosine ,
dihydroergotamine ,
ergoloid (dihydroergotoxine) )
DS2
Efavirenz
Etazepine
Etifoxine
Fenamates (e.g.,
flufenamic acid ,
mefenamic acid ,
niflumic acid ,
tolfenamic acid )
Fluoxetine
Flupirtine
Hopantenic acid
KRM-II-81
Lanthanum
Lavender oil
Lignans (e.g.,
4-O-methylhonokiol ,
honokiol ,
magnolol ,
obovatol )
Loreclezole
Menthyl isovalerate (validolum)
Monastrol
Niacin
Niacinamide
Org 25,435
Phenytoin
Propanidid
Retigabine (ezogabine)
Safranal
Seproxetine
Stiripentol
Sulfonylalkanes (e.g.,
sulfonmethane (sulfonal) ,
tetronal ,
trional )
Terpenoids (e.g.,
borneol )
Topiramate
Valerian constituents (e.g.,
isovaleric acid ,
isovaleramide ,
valerenic acid ,
valerenol )