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Buthalital
Clinical data
ATC code
  • None
Identifiers
  • sodium 5-allyl-5-isobutyl-6-oxo-2-thioxo-1,2,5,6-tetrahydro-4-pyrimidinolate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard ( EPA)
Chemical and physical data
FormulaC11H15N2NaO2S
Molar mass262.30 g·mol−1
3D model ( JSmol)
  • [Na+].O=C1NC(=S)/N=C(/[O-])C1(CC(C)C)C\C=C
  • InChI=1S/C11H16N2O2S.Na/c1-4-5-11(6-7(2)3)8(14)12-10(16)13-9(11)15;/h4,7H,1,5-6H2,2-3H3,(H2,12,13,14,15,16);/q;+1/p-1
  • Key:APSWQQYXFMUODF-UHFFFAOYSA-M

Buthalital sodium ( INN; Bayinal, Baytinal, Thialbutal, Transithal, Ulbreval), or buthalitone sodium ( BAN), is a barbiturate derivative which was under development as a short-acting anesthetic. [1] [2] However, development was discontinued, perhaps due to its extremely rapid elimination rate, [3] and buthalital sodium was never marketed. [1]

See also

References

  1. ^ a b Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. 338. ISBN  978-0-412-46630-4. Retrieved 19 May 2012.
  2. ^ Martin JR, Godel T, Hunkeler W, Jenck F, Moreau JL, Sleight AJ, Widmer U (2000). "Psychopharmacological Agents". Kirk-Othmer Encyclopedia of Chemical Technology. doi: 10.1002/0471238961.1619250313011820.a01. ISBN  0471238961.
  3. ^ Wollweber H (2000). "Anesthetics, General". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi: 10.1002/14356007.a02_289. ISBN  978-3527306732.