From Wikipedia, the free encyclopedia
Anxiolytic drug
ICI-190,622
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4-Amino-1-pent-3-ynyl-N-prop-2-enylpyrazolo[3,4-b]pyridine-5-carboxamide
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PubChem
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CompTox Dashboard (
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Formula | C15H17N5O |
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Molar mass | 283.335 g·mol−1 |
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3D model (
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CC#CCCN1C2=NC=C(C(=C2C=N1)N)C(=O)NCC=C
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InChI=1S/C15H17N5O/c1-3-5-6-8-20-14-11(10-19-20)13(16)12(9-18-14)15(21)17-7-4-2/h4,9-10H,2,6-8H2,1H3,(H2,16,18)(H,17,21) NKey:ZPOHUNITDKKDQD-UHFFFAOYSA-N N
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NY
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ICI-190,622 is an
anxiolytic drug used in scientific research. It is a
pyrazolopyridine derivative, related to other anxiolytic compounds such as
tracazolate, and more distantly to
zaleplon. It has similar effects to
benzodiazepine drugs, but is structurally distinct and so is classed as a
nonbenzodiazepine anxiolytic.
[1]
[2]
See also
References
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^
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^ Bare TM, McLaren CD, Campbell JB, Firor JW, Resch JF, Walters CP, Salama AI, Meiners BA, Patel JB (December 1989). "Synthesis and structure-activity relationships of a series of anxioselective pyrazolopyridine ester and amide anxiolytic agents". Journal of Medicinal Chemistry. 32 (12): 2561–73.
doi:
10.1021/jm00132a011.
PMID
2573731.
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Piperidinediones | |
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Pyrazolopyridines | |
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Quinazolinones | |
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Volatiles/
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Others/unsorted |
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3-Hydroxybutanal
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α-EMTBL
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AA-29504
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KRM-II-81
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Org 25,435
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