2C-T-2 is a
psychedelic and
entactogenicphenethylamine of the
2C family.[1] It was first synthesized in 1981 by
Alexander Shulgin, and rated by him as one of the "magical half-dozen" most important psychedelic phenethylamine compounds.[2][3] The drug has structural and pharmacodynamic properties similar to those of
2C-T-7 ("Blue Mystic").
A potential risk of
neurotoxicity from 2C-T-2 use (and 2C chemical series in general) has been shown in serotonergic and
dopaminergic containing neurons.[8] This has also been shown to be magnified in serotonergic-containing cells with combined use of 2C series drugs with alcohol,
MDMA, and
methamphetamine.[9]
2C-T-2 is also a controlled substance in Argentina as well as
2C-B and
2C-I.[11]
Canada
As of October 31, 2016, 2C-T-2 is a controlled substance (Schedule III) in Canada.[12]
China
As of October 2015 2C-T-2 is a controlled substance in China.[13]
Netherlands
The Netherlands became the first country in the world to ban 2C-T-2, and classify it as a hard drug, by law. In April, 1999, 2C-T-2 became a list I drug of the
Opium Law.
Sweden
Schedule I in Sweden.
2C-T-2 was first classified as "health hazard" under the act
Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of April 1, 1999, under SFS 1999:58[14] that made it illegal to sell or possess.
The Riksdag added 2C-T-2 to
Narcotic Drugs Punishments Act under Swedish schedule I ("substances, plant materials and fungi which normally do not have medical use") as of March 16, 2004, published by
Medical Products Agency (MPA) in regulation LVFS 2004:3 listed as 2C-T-2, 2,5-dimetoxi-4-etyltiofenetylamin.[15]
United Kingdom
2C-T-2 and all other compounds featured in
PiHKAL are illegal drugs in the
United Kingdom.
2C-T-2 is considered a Schedule 9 prohibited substance in Australia under the
Poisons Standard (October 2015).[17] A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities.[17]
^Theobald DS, Staack RF, Puetz M, Maurer HH (September 2005). "New designer drug 2,5-dimethoxy-4-ethylthio-beta-phenethylamine (2C-T-2): studies on its metabolism and toxicological detection in rat urine using gas chromatography/mass spectrometry". Journal of Mass Spectrometry. 40 (9): 1157–1172.
Bibcode:
2005JMSp...40.1157T.
doi:
10.1002/jms.890.
PMID16041763.
^"关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from
the original on 1 October 2015. Retrieved 1 October 2015.
^
ab"Poisons Standard October 2015". Federal Register of Legislation. Australian Government, Department of Health, Therapeutic Goods Administration. October 2015.