FUB-APINACA (also known as A-FUBINACA according to the EMCCDA framework for naming synthetic cannabinoids[1] and FUB-AKB48) is an
indazole-based
synthetic cannabinoid that is presumed to be a potent
agonist of the
CB1 receptor and has been sold online as a
designer drug.[2] It is an analog of
APINACA and
5F-APINACA where the pentyl chain has been replaced with fluorobenzyl.
In the United States, FUB-APINACA was temporarily emergency scheduled by the DEA in 2019.[4] and made a permanent
Schedule I Controlled Substance nationwide on April 7, 2022.[5] Previously, it was illegal only in
Alabama (listed as FUB-AKB48).[6]
Sweden's public health agency suggested classifying FUB-APINACA as a hazardous substance on November 10, 2014.[7]
^ Pulver B, Fischmann S, Gallegos A,
Christie R. EMCDDA framework and practical guidance for
naming synthetic cannabinoids. Drug Test Anal. 2023;15(3):
255‐276. doi:10.1002/dta.3403
^"FUB-AKB48". Cayman Chemical. Retrieved 23 July 2015.