From Wikipedia, the free encyclopedia
Chemical compound
Azatadine (Optimine ) is a
first-generation antihistamine and
anticholinergic drug that was synthesized in 1963 by
Schering-Plough , a former American pharmaceutical company.
[1]
[2]
It was patented in 1967.
[3] It has been succeeded by both
loratadine and
desloratadine .
[4] : 53 and marketing approvals have been widely withdrawn.
[5]
[6]
[7]
[8] : 290
[9]
See also
References
^ Katelaris C (December 1990). "Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis". Asian Pacific Journal of Allergy and Immunology . 8 (2): 103–7.
PMID
1982614 .
^ Small P, Barrett D, Biskin N (February 1990). "Effects of azatadine, terfenadine, and astemizole on allergen-induced nasal provocation". Annals of Allergy . 64 (2 Pt 1): 129–31.
PMID
1968324 .
^
US 3326924 , Villani FJ, Caldwell W, "Azatadine", issued 1967
^ Horak F (2010). "Antialergic and Vasoactive Drugs for Allergic Rhinitis. Chapter 4". In Pawankar R, Holgate ST, Rosenwasser LJ (eds.). Allergy Frontiers:Therapy and Prevention . Vol. 5. Springer Science & Business Media.
ISBN
9784431993629 .
^
"Azatadine" . Drugs.com .
^ Food and Drug Administration (2005).
"Docket No.2005N-0058: Hospira, Inc. et al.; Withdrawal of Approval of 76 New Drug Applications and 60 Abbreviated New Drug Applications" . Federal Register 70 FR 10651 .
^ Food and Drug Administration (2007).
"Docket No. 2004P-0262: Withdrawal of Approval of 128 Suitability Petitions" . Federal Register 72 FR 8184 .
^
"Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals" (PDF) . Department of Economic and Social Affairs of the United Nations Secretariat . New York: United Nations. 2005.
^
"OGD Suitability Tracking Report (Sorted by Drug Name)" . FDA .
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