Histapyrrodine References

Histapyrrodine
Clinical data
Routes of; administration	Oral
ATC code	R06AC02 ( WHO) ; R06AC52 ( WHO) (combinations);
Identifiers
	IUPAC name N-benzyl-N-(2-pyrrolidin-1-ylethyl)aniline;
CAS Number	493-80-1 ;
PubChem CID	68122;
ChemSpider	61430 ;
UNII	0FYM61NG4D;
KEGG	D07400 ;
ChEMBL	ChEMBL2105039;
CompTox Dashboard ( EPA)	DTXSID20197764 ;
ECHA InfoCard	100.007.075
Chemical and physical data
Formula	C19H24N2
Molar mass	280.415 g·mol−1
3D model ( JSmol)	Interactive image;
	SMILES N(c1ccccc1)(Cc2ccccc2)CCN3CCCC3;
	InChI InChI=1S/C19H24N2/c1-3-9-18(10-4-1)17-21(19-11-5-2-6-12-19)16-15-20-13-7-8-14-20/h1-6,9-12H,7-8,13-17H2 ; Key:MXHODDGKGSGCDI-UHFFFAOYSA-N ;
	(verify)

Histapyrrodine is an antihistamine with anticholinergic properties.^[1]

References

^ Sigwald J, Raymondeaud C (January 1957). "[Neurosedative action of histapyrrodine; its therapeutic value in anxiety, neurotonic manifestations and states of aggression]". Semaine Médicale Professionelle et Médico-Sociale (in French). 33 (4): 161–2. PMID 13421807.

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[1] Sigwald J, Raymondeaud C (January 1957). "[Neurosedative action of histapyrrodine; its therapeutic value in anxiety, neurotonic manifestations and states of aggression]". Semaine Médicale Professionelle et Médico-Sociale (in French). 33 (4): 161–2. PMID 13421807.

[1]

v t e Antihistamines ( R06)
Benzimidazoles ( *)	Astemizole Azelastine Bilastine Emedastine Mizolastine Talastine
Diarylmethanes	Diarylmethoxyalkylamines: Bromazine (bromodiphenhydramine) Carbinoxamine Chlorphenoxamine Clemastine Diphenhydramine ( +naproxen) Diphenylpyraline Doxylamine Ebastine Orphenadrine Diphenylmethanolpiperidines: Fexofenadine Terfenadine Diphenylmethylpiperazines: Buclizine Cetirizine Levocetirizine Chlorcyclizine Cinnarizine Cyclizine Etodroxizine Hydroxyzine Meclizine Oxatomide Phenylpyridinylpropanamines: Brompheniramine Chlorphenamine Dexbrompheniramine ( +pseudoephedrine) Dexchlorpheniramine ( +betamethasone) Pheniramine Others: Acrivastine Bamipine Dimetindene Phenyltoloxamine Pyrrobutamine Quifenadine Triprolidine
Ethylenediamines	Antazoline Chloropyramine Histapyrrodine Mepyramine (pyrilamine) Methapyrilene Phenbenzamine Thenalidine Tripelennamine (pyribenzamine)
Tricyclics	Dibenzocycloheptenes: Antidepressants (e.g., amitriptyline) Azatadine Cyproheptadine Deptropine Desloratadine Ketotifen Loratadine Rupatadine Phenothiazines: Alimemazine Fenethazine Hydroxyethylpromethazine Isothipendyl Mequitazine Methdilazine Oxomemazine Promethazine Others: Antidepressants (e.g., doxepin, mirtazapine, trimipramine) Epinastine Latrepirdine Mebhydrolin Olopatadine Perlapine Phenindamine Pimethixene
Others	Phenylpiperazines: Antidepressants (e.g., trazodone) Phenbenzamine
For topical use	Bamipine Chloropyramine Chlorphenoxamine Clemastine Dimetindene Diphenhydramine Doxepin Isothipendyl Mepyramine (pyrilamine) Promethazine

Clinical data

Routes of administration	Oral
ATC code	R06AC02 ( WHO) R06AC52 ( WHO) (combinations)
Identifiers
IUPAC name N-benzyl-N-(2-pyrrolidin-1-ylethyl)aniline
CAS Number	493-80-1^Y
PubChem CID	68122
ChemSpider	61430^Y
UNII	0FYM61NG4D
KEGG	D07400^Y
ChEMBL	ChEMBL2105039
CompTox Dashboard ( EPA)	DTXSID20197764
ECHA InfoCard	100.007.075
Chemical and physical data
Formula	C₁₉H₂₄N₂
Molar mass	280.415 g·mol⁻¹
3D model ( JSmol)	Interactive image
SMILES N(c1ccccc1)(Cc2ccccc2)CCN3CCCC3
InChI InChI=1S/C19H24N2/c1-3-9-18(10-4-1)17-21(19-11-5-2-6-12-19)16-15-20-13-7-8-14-20/h1-6,9-12H,7-8,13-17H2^Y Key:MXHODDGKGSGCDI-UHFFFAOYSA-N^Y
(verify)