From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Interleukin 10 receptor, beta subunit is a subunit for the
interleukin-10 receptor . IL10RB is its human
gene .
[5]
IL10RB has also been designated CDw210b (
cluster of differentiation w210b).
The protein encoded by this gene belongs to the
cytokine receptor family. It is an accessory chain essential for the active
interleukin 10 receptor complex. Coexpression of this and
IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes,
IFNAR2 ,
IFNAR1 , and
IFNGR2 , form a
class II cytokine receptor gene cluster located in a small region on chromosome 21.
[5]
References
Further reading
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This article incorporates text from the
United States National Library of Medicine , which is in the
public domain .
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