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Drug given during chemotherapy to increase blood cell regeneration
Promegapoietin is a drug given during
chemotherapy to increase
blood cell regeneration. It is a
colony-stimulating factor that stimulates
megakaryocyte production.
[1]
[2]
It functions by stimulating ligands for
interleukin 3 and
c-Mpl.
[3]
References
-
^
-
^
Definition of promegapoietin – NCI Dictionary of Cancer Terms
-
^ Doshi P, Giri J, Abegg A, Favara J, Huynh M, Kahn L, Minnerly J, Pegg L, Villani-Price D, Siegel N, Staten N, Thomas J, McKearn J, Smith W (2001).
"Promegapoietin, a family of chimeric growth factors, supports megakaryocyte development through activation of IL-3 and c-Mpl ligand signaling pathways". Exp Hematol. 29 (10): 1177–84.
doi:
10.1016/S0301-472X(01)00694-4.
PMID
11602319.
External links
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Chemokine | |
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CSF | |
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Interferon |
IFNAR (α/β, I) |
- Agonists:
Albinterferon
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Interferon alpha (interferon alfa, IFN-α)
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Interferon alfa (
IFNA1,
IFNA2,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA21)
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Interferon alfa 2a
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Interferon alfa 2b
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Interferon alfa n1
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Interferon alfacon-1
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Interferon alpha-n3
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Interferon beta (IFN-β) (
IFNB1,
IFNB3)
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Interferon beta 1a
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Interferon beta 1b
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Interferon kappa (IFN-ε/κ/τ/ζ, IFNK)
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Interferon omega (IFN-ω, IFNW1)
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Peginterferon alfa-2a
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Peginterferon alfa-2b
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IFNGR (γ, II) | |
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IFNLR (λ, III) |
- See IL-28R (IFNLR)
here instead.
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Interleukin | |
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TGFβ | |
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TNF | |
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Others | |
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