Clinical data | |
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Other names | Δ1-Testosterone; 1-Dehydrotestosterone; RU-18761; Androsta-1,4-dien-17β-ol-3-one |
AHFS/ Drugs.com | International Drug Names |
Pregnancy category | |
Routes of administration | Intramuscular injection |
Drug class | Androgen; Anabolic steroid |
ATC code |
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Legal status | |
Legal status |
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Pharmacokinetic data | |
Elimination half-life | Intramuscular: 14 days (as boldenone undecylenate) [2] |
Identifiers | |
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CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
ChEBI | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.011.533 |
Chemical and physical data | |
Formula | C19H26O2 |
Molar mass | 286.415 g·mol−1 |
3D model ( JSmol) | |
Melting point | 165 °C (329 °F) |
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Boldenone (developmental code name RU-18761), is a naturally occurring anabolic–androgenic steroid (AAS) and the 1(2)- dehydrogenated analogue of testosterone. [3] [4] [5] [6] [7] Boldenone itself has never been marketed; as a pharmaceutical drug, it is used as boldenone undecylenate, the undecylenate ester. [3] [4] [7]
Like other AAS, boldenone is an agonist of the androgen receptor (AR). [7] The activity of boldenone is mainly anabolic, with a low androgenic potency. Boldenone will increase nitrogen retention, protein synthesis, increases appetite and stimulates the release of erythropoietin in the kidneys. [8]
Boldenone, also known as Δ1-testosterone, 1-dehydrotestosterone, or androsta-1,4-dien-17β-ol-3-one, is a naturally occurring androstane steroid and a derivative of testosterone. [3] [4] [7] It is specifically testosterone with a double bond between the C1 and C2 positions. [3] [4] [7] A related compound is quinbolone, the 17- cyclopentenyl enol ether of boldenone. [3] [4]
Boldenone occurs naturally in the scent gland of Ilybius fenestratus, a species of aquatic beetle. [3]
Ciba reportedly patented boldenone in 1949. [7] It subsequently developed several experimental esters of the drug in the 1950s and 1960s. [7] One of these was boldenone undecylenate, which was introduced for clinical use under the brand name Parenabol and saw some use in the late 1960s and early 1970s. [7] However, it was discontinued before the end of the 1970s. [7] Subsequently, boldenone undecylenate was introduced by Squibb under the brand name Equipose for veterinary use, most commonly in horses. [7]
Boldenone is the generic name of the drug and its INN and BAN . [3] [4] [5] [6]
Boldenone is marketed as veterinary drug as boldenone undecylenate (a derivative of boldenone) under the following brand names: Boldebal H, Equipoise, and Sybolin. [6] It is marketed as a veterinary combination drug with methandriol under the brand name Drive. [6]
In Ukraine, it is marketed for human consumption as the injectable steroid Boldenol. [9]
There are many known cases of doping in sports with boldenone undecylenate by professional athletes.