Topterone (
INNTooltip International Nonproprietary Name,
USANTooltip United States Adopted Name) (developmental code name WIN-17665), also known as 17α-propyltestosterone (or simply propyltestosterone) or as 17α-propylandrost-4-en-17β-ol-3-one, is a
steroidal antiandrogen that was first reported in 1978 and was developed for
topical administration but, due to poor effectiveness, was never marketed.[1][2][3][4][5][6]
^Ferrari RA, Chakrabarty K, Creange JE, Beyler AL, Potts OG, Schane HP (April 1980). "Endocrine profile of topterone, a topical antiandrogen, in three species of laboratory animals". Methods and Findings in Experimental and Clinical Pharmacology. 2 (2): 65–69.
PMID7339330.
^Marsden JR, Shuster S (6 December 2012).
"The Treatment of Acne". Pharmacology of the Skin II: Methods, Absorption, Metabolism and Toxicity, Drugs and Diseases. Springer Science & Business Media. pp. 490–.
ISBN978-3-642-74054-1.