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Androvax
Combination of
Androstendione Androstane steroid
Human serum albumin Serum protein
Clinical data
Trade namesAndrovax
Other namesAndrostenedione:human serum albumin conjugate
AHFS/ Drugs.com Monograph
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
  • None

Androvax, also known as androstenedione:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine to increase the ovulation rate and number of lambs born to ewes. [1] [2] [3] It is a conjugate of androstenedione and human serum albumin. [1] [3] The drug is marketed in New Zealand. [1] [3]

Androvax produces immunity against androstenedione, and the generation of antibodies against androstenedione decreases circulating levels of androstenedione. [1] In addition, since androstenedione is the major precursor of estrogens, estrogen levels are decreased as well. [1] This is thought to result in reduced negative feedback on the hypothalamic-pituitary-gonadal axis and increased gonadotropin secretion, which in turn improves fertility and fecundity. [1]

See also

References

  1. ^ a b c d e f Jindal SK, Sharma MC (2010). Biotechnology in Animal Health and Production. New India Publishing. pp. 77–. ISBN  978-93-80235-35-6.
  2. ^ Reproductive Technologies in Farm Animals. CABI. 2004. pp. 206–. ISBN  978-0-85199-049-1.
  3. ^ a b c "Androvax Label" (PDF). Schering-Plough Animal Health Ltd. MSD Animal Health.



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