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Chemical compound
4-Keto-PCP
4-phenyl-4-piperidin-1-ylcyclohexan-1-one
CAS Number
PubChem
CID
Formula C 17 H 23 N O
Molar mass 257.377 g·mol−1 3D model (
JSmol )
C1CCN(CC1)C2(CCC(=O)CC2)C3=CC=CC=C3
InChI=1S/C17H23NO/c19-16-9-11-17(12-10-16,15-7-3-1-4-8-15)18-13-5-2-6-14-18/h1,3-4,7-8H,2,5-6,9-14H2
Key:HBVUBDNRZWJTSB-UHFFFAOYSA-N
4-Keto-PCP is a recreational
designer drug from the
arylcyclohexylamine family, with
dissociative effects. It has potency in between that of
ketamine and
phencyclidine but with somewhat more sedating effects in animal studies.
[1]
See also
References
^ Ortiz DM, Custodio RJ, Abiero A, Botanas CJ, Sayson LV, Kim M, Lee HJ, Kim HJ, Jeong Y, Yoon S, Lee YS, Cheong JH (November 2020). "The dopaminergic alterations induced by 4-F-PCP and 4-Keto-PCP may enhance their drug-induced rewarding and reinforcing effects: Implications for abuse". Addiction Biology . 26 (4): e12981.
doi :
10.1111/adb.12981 .
PMID
33135332 .
S2CID
226234538 .
AMPAR Tooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
KAR Tooltip Kainate receptor
NMDAR Tooltip N-Methyl-D-aspartate receptor
Group I
mGluR1 Tooltip Metabotropic glutamate receptor 1
mGluR5 Tooltip Metabotropic glutamate receptor 5
Group II
mGluR2 Tooltip Metabotropic glutamate receptor 2
mGluR3 Tooltip Metabotropic glutamate receptor 3
Group III
mGluR4 Tooltip Metabotropic glutamate receptor 4
mGluR6 Tooltip Metabotropic glutamate receptor 6
mGluR7 Tooltip Metabotropic glutamate receptor 7
mGluR8 Tooltip Metabotropic glutamate receptor 8