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Other names | McN-485 |
Routes of administration | Oral |
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Formula | C7H5ClN2O |
Molar mass | 168.58 g·mol−1 |
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Zoxazolamine ( INN, USAN, BAN) (brand name Contrazole, Deflexol, Flexin, Miazol, Uri-Boi, Zoxamine, Zoxine) is a muscle relaxant that is no longer marketed. [1] [2] It was synthesized in 1953 and introduced clinically in 1955 but was withdrawn due to hepatotoxicity. [1] [2] [3] One of its active metabolites, chlorzoxazone, was found to show less toxicity, and was subsequently marketed in place of zoxazolamine. [3] These drugs activate IKCa channels. [4]