From Wikipedia, the free encyclopedia
Riodipine
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Names
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Preferred IUPAC name
Dimethyl 4-[2-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
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Identifiers
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ChemSpider
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MeSH
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C045912
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UNII
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InChI=1S/C18H19F2NO5/c1-9-13(16(22)24-3)15(14(10(2)21-9)17(23)25-4)11-7-5-6-8-12(11)26-18(19)20/h5-8,15,18,21H,1-4H3 NKey: AZVFIZVKGSPGPK-UHFFFAOYSA-N NInChI=1/C18H19F2NO5/c1-9-13(16(22)24-3)15(14(10(2)21-9)17(23)25-4)11-7-5-6-8-12(11)26-18(19)20/h5-8,15,18,21H,1-4H3 Key: AZVFIZVKGSPGPK-UHFFFAOYAO
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CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2OC(F)F)C(=O)OC
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Properties
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C18H19F2NO5
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Molar mass
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367.349 g·mol−1
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Riodipine (
INN; brand names Foridon and Ryosidine) is a
calcium channel blocker.
[1]
References
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Calcium |
VDCCsTooltip Voltage-dependent calcium channels | |
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Potassium |
VGKCsTooltip Voltage-gated potassium channels | |
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IRKsTooltip Inwardly rectifying potassium channel | |
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KCaTooltip Calcium-activated potassium channel | |
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K2PsTooltip Tandem pore domain potassium channel | |
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Sodium |
VGSCsTooltip Voltage-gated sodium channels | |
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ENaCTooltip Epithelial sodium channel | |
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ASICsTooltip Acid-sensing ion channel | |
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Chloride |
CaCCsTooltip Calcium-activated chloride channel | |
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CFTRTooltip Cystic fibrosis transmembrane conductance regulator | |
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Unsorted | |
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Others |
TRPsTooltip Transient receptor potential channels | |
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LGICsTooltip Ligand gated ion channels | |
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CARTooltip Constitutive androstane receptor | |
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PXRTooltip Pregnane X receptor | |
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