From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
TUBB1 is a
gene that codes for the
protein Tubulin beta-1 chain in humans.
[5]
References
Further reading
Watts NR, Sackett DL, Ward RD, et al. (2000).
"HIV-1 Rev Depolymerizes Microtubules to Form Stable Bilayered Rings" . J. Cell Biol . 150 (2): 349–60.
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10.1083/jcb.150.2.349 .
PMC
2180222 .
PMID
10908577 .
Deloukas P, Matthews LH, Ashurst J, et al. (2002).
"The DNA sequence and comparative analysis of human chromosome 20" . Nature . 414 (6866): 865–71.
Bibcode :
2001Natur.414..865D .
doi :
10.1038/414865a .
PMID
11780052 .
Andersen JS, Lyon CE, Fox AH, et al. (2002).
"Directed proteomic analysis of the human nucleolus" . Curr. Biol . 12 (1): 1–11.
doi :
10.1016/S0960-9822(01)00650-9 .
PMID
11790298 .
S2CID
14132033 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Chen D, Wang M, Zhou S, Zhou Q (2004).
"HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim" . EMBO J . 21 (24): 6801–10.
doi :
10.1093/emboj/cdf683 .
PMC
139103 .
PMID
12486001 .
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol . 21 (5): 566–9.
doi :
10.1038/nbt810 .
PMID
12665801 .
S2CID
23783563 .
Yanagida M, Hayano T, Yamauchi Y, et al. (2004).
"Human fibrillarin forms a sub-complex with splicing factor 2-associated p32, protein arginine methyltransferases, and tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ribonucleoprotein complexes" . J. Biol. Chem . 279 (3): 1607–14.
doi :
10.1074/jbc.M305604200 .
PMID
14583623 .
Dou Z, Ding X, Zereshki A, et al. (2004). "TTK kinase is essential for the centrosomal localization of TACC2". FEBS Lett . 572 (1–3): 51–6.
doi :
10.1016/j.febslet.2004.06.092 .
PMID
15304323 .
S2CID
8403635 .
Schulze H, Korpal M, Bergmeier W, et al. (2005).
"Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions" . Blood . 104 (13): 3949–57.
doi :
10.1182/blood-2004-03-1179 .
PMID
15315966 .
Campbell GR, Pasquier E, Watkins J, et al. (2005).
"The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis" . J. Biol. Chem . 279 (46): 48197–204.
doi :
10.1074/jbc.M406195200 .
PMID
15331610 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
de Mareuil J, Carre M, Barbier P, et al. (2006).
"HIV-1 Tat protein enhances Microtubule polymerization" . Retrovirology . 2 : 5.
doi :
10.1186/1742-4690-2-5 .
PMC
549075 .
PMID
15691386 .
Giacca M (2006).
"HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?" . Retrovirology . 2 : 7.
doi :
10.1186/1742-4690-2-7 .
PMC
549042 .
PMID
15698476 .
Freson K, De Vos R, Wittevrongel C, et al. (2005).
"The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure" . Blood . 106 (7): 2356–62.
doi :
10.1182/blood-2005-02-0723 .
PMID
15956286 .
Mesquita B, Veiga I, Pereira D, et al. (2006).
"No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin" . BMC Cancer . 5 : 101.
doi :
10.1186/1471-2407-5-101 .
PMC
1199587 .
PMID
16095531 .
Coiras M, Camafeita E, Ureña T, et al. (2006). "Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression". Proteomics . 6 (Suppl 1): S63–73.
doi :
10.1002/pmic.200500437 .
PMID
16526095 .
S2CID
42878271 .
Navarro-Núñez L, Lozano ML, Rivera J, et al. (2007).
"The association of the beta1-tubulin Q43P polymorphism with intracerebral hemorrhage in men" . Haematologica . 92 (4): 513–8.
doi :
10.3324/haematol.10689 .
PMID
17488662 .