Dynein, light chain, Tctex-type 3, also known as DYNLT3, is a
protein which in humans is encoded by the DYNLT3gene.[5][6]
Function
DYNLT3 is a member of the
dynein motor protein family. DYNLT3 binds to
BUB3, a
spindle checkpoint protein is present on
kinetochores at
prometaphase.[7] DYNLT3 can also function as a transcription regulator of
Bcl-2 gene through binding to
SATB1 in a dynein-independent manner.[8]
^Roux AF, Rommens J, McDowell C, Anson-Cartwright L, Bell S, Schappert K, Fishman GA, Musarella M (February 1994). "Identification of a gene from Xp21 with similarity to the tctex-1 gene of the murine t complex". Hum. Mol. Genet. 3 (2): 257–63.
doi:
10.1093/hmg/3.2.257.
PMID8004092.
^Schwarzer, Christian; Barnikol-Watanabe Shitsu; Thinnes Friedrich P; Hilschmann Norbert (Sep 2002). "Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74". Int. J. Biochem. Cell Biol. 34 (9): 1059–70.
doi:
10.1016/S1357-2725(02)00026-2.
ISSN1357-2725.
PMID12009301.
S2CID11632830.
Further reading
Roux AF, Rommens J, McDowell C, et al. (1994). "Identification of a gene from Xp21 with similarity to the tctex-1 gene of the murine t complex". Hum. Mol. Genet. 3 (2): 257–63.
doi:
10.1093/hmg/3.2.257.
PMID8004092.