From Wikipedia, the free encyclopedia
Cell surface protein binding somatostatin and triggering intracellular changes
Somatostatin receptors are receptors for the
ligand
somatostatin, a small
neuropeptide associated with neural signaling, particularly in the
post-synaptic response to
NMDA receptor co-stimulation/activation. Somatostatin is encoded by a CRE and is very susceptible to gene
promoter region activation by
transcription factor
CREB.
[1]
There are five known somatostatin receptors:
[2]
All are
G protein-coupled
seven transmembrane receptors.
References
-
^ Lou L (2016). Principles of Neurobiology. New York, NY: Garland Science, Taylor and Francis Group. pp. 109–110.
ISBN
978-0-8153-4494-0.
-
^ Hoyer D, Bell GI, Berelowitz M, Epelbaum J, Feniuk W, Humphrey PP, O'Carroll AM, Patel YC, Schonbrunn A, Taylor JE (1995).
"Classification and nomenclature of somatostatin receptors". Trends Pharmacol. Sci. 16 (3): 86–8.
doi:
10.1016/S0165-6147(00)88988-9.
PMID
7792934.
External links