From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
G protein-coupled receptor 1 , also known as GPR1 , is a
protein that in humans is encoded by the GPR1
gene .
[5]
[6]
GPR1 is a member of the
G protein-coupled receptor family of transmembrane receptors. It functions as a receptor for
chemerin .
[7] Other receptors for chemerin include
CMKLR1 and
CCRL2 .
References
^
a
b
c
ENSG00000283448 GRCh38: Ensembl release 89: ENSG00000183671, ENSG00000283448 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000046856 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Entrez Gene: GPR1 G protein-coupled receptor 1" .
^ Marchese A, Docherty JM, Nguyen T, Heiber M, Cheng R, Heng HH, Tsui LC, Shi X, George SR, O'Dowd BF (October 1994). "Cloning of human genes encoding novel G protein-coupled receptors". Genomics . 23 (3): 609–18.
doi :
10.1006/geno.1994.1549 .
PMID
7851889 .
^ Barnea G, Strapps W, Herrada G, Berman Y, Ong J, Kloss B, Axel R, Lee KJ (January 2008).
"The genetic design of signaling cascades to record receptor activation" . Proc. Natl. Acad. Sci. U.S.A . 105 (1): 64–9.
doi :
10.1073/pnas.0710487105 .
PMC
2224232 .
PMID
18165312 .
Further reading
Shimizu N, Soda Y, Kanbe K, et al. (1999).
"An Orphan G Protein-Coupled Receptor, GPR1, Acts as a Coreceptor To Allow Replication of Human Immunodeficiency Virus Types 1 and 2 in Brain-Derived Cells" . J. Virol . 73 (6): 5231–9.
doi :
10.1128/JVI.73.6.5231-5239.1999 .
PMC
112576 .
PMID
10233994 .
Tokizawa S, Shimizu N, Hui-Yu L, et al. (2000).
"Infection of mesangial cells with HIV and SIV: identification of GPR1 as a coreceptor" . Kidney Int . 58 (2): 607–17.
doi :
10.1046/j.1523-1755.2000.00207.x .
PMID
10916084 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Kang MK, Kameta A, Shin KH, et al. (2003). "Senescence-associated genes in normal human oral keratinocytes". Exp. Cell Res . 287 (2): 272–81.
doi :
10.1016/S0014-4827(03)00061-2 .
PMID
12837283 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Hillier LW, Graves TA, Fulton RS, et al. (2005).
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4" . Nature . 434 (7034): 724–31.
Bibcode :
2005Natur.434..724H .
doi :
10.1038/nature03466 .
PMID
15815621 .
Jinno-Oue A, Shimizu N, Soda Y, et al. (2005).
"The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 HIV-1" . J. Biol. Chem . 280 (35): 30924–34.
doi :
10.1074/jbc.M500195200 .
PMID
15919664 .
Otsuki T, Ota T, Nishikawa T, et al. (2007).
"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries" . DNA Res . 12 (2): 117–26.
doi :
10.1093/dnares/12.2.117 .
PMID
16303743 .
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
"Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55–65.
doi :
10.1101/gr.4039406 .
PMC
1356129 .
PMID
16344560 .