From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Relaxin/insulin-like family peptide receptor 4, also known as RXFP4, is a human
G-protein coupled receptor.
[5]
Function
GPR100 is a member of the
rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003).[supplied by
OMIM
[5]
See also
References
External links
Further reading
- Bathgate RA, Ivell R, Sanborn BM, Sherwood OD, Summers RJ (May 2005). "Receptors for relaxin family peptides". Annals of the New York Academy of Sciences. 1041 (1): 61–76.
Bibcode:
2005NYASA1041...61B.
doi:
10.1196/annals.1282.010.
PMID
15956688.
S2CID
1185573.
- Bathgate RA, Ivell R, Sanborn BM, Sherwood OD, Summers RJ (March 2006). "International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides". Pharmacological Reviews. 58 (1): 7–31.
doi:
10.1124/pr.58.1.9.
PMID
16507880.
S2CID
7466039.
- Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S (June 2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Letters. 520 (1–3): 97–101.
doi:
10.1016/S0014-5793(02)02775-8.
PMID
12044878.
S2CID
7116392.
- Liu C, Chen J, Sutton S, Roland B, Kuei C, Farmer N, Sillard R, Lovenberg TW (December 2003).
"Identification of relaxin-3/INSL7 as a ligand for GPCR142". The Journal of Biological Chemistry. 278 (50): 50765–70.
doi:
10.1074/jbc.M308996200.
PMID
14522967.
- Boels K, Schaller HC (November 2003).
"Identification and characterisation of GPR100 as a novel human G-protein-coupled bradykinin receptor". British Journal of Pharmacology. 140 (5): 932–8.
doi:
10.1038/sj.bjp.0705521.
PMC
1574110.
PMID
14530218.
- Fredriksson R, Höglund PJ, Gloriam DE, Lagerström MC, Schiöth HB (November 2003).
"Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives". FEBS Letters. 554 (3): 381–8.
doi:
10.1016/S0014-5793(03)01196-7.
PMID
14623098.
S2CID
11563502.
- Liu C, Chen J, Kuei C, Sutton S, Nepomuceno D, Bonaventure P, Lovenberg TW (January 2005). "Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7". Molecular Pharmacology. 67 (1): 231–40.
doi:
10.1124/mol.104.006700.
PMID
15465925.
S2CID
25164369.
- Liu C, Kuei C, Sutton S, Chen J, Bonaventure P, Wu J, Nepomuceno D, Kamme F, Tran DT, Zhu J, Wilkinson T, Bathgate R, Eriste E, Sillard R, Lovenberg TW (January 2005).
"INSL5 is a high affinity specific agonist for GPCR142 (GPR100)". The Journal of Biological Chemistry. 280 (1): 292–300.
doi:
10.1074/jbc.M409916200.
PMID
15525639.
This article incorporates text from the
United States National Library of Medicine, which is in the
public domain.