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COX-2 selective NSAID veterinary drug
Robenacoxib
Trade names Onsior
License data
ATCvet code
Legal status
{5-Ethyl-2-[(2,3,5,6-tetrafluorophenyl)amino]phenyl}acetic acid
CAS Number
PubChem
CID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (
EPA )
ECHA InfoCard
100.210.035
Formula C 16 H 13 F 4 N O 2
Molar mass 327.279 g·mol−1 3D model (
JSmol )
O=C(O)Cc2c(Nc1c(F)c(F)cc(F)c1F)ccc(c2)CC
InChI=1S/C16H13F4NO2/c1-2-8-3-4-12(9(5-8)6-13(22)23)21-16-14(19)10(17)7-11(18)15(16)20/h3-5,7,21H,2,6H2,1H3,(H,22,23)
Key:ZEXGDYFACFXQPF-UHFFFAOYSA-N
Robenacoxib , sold under the brand name Onsior , is a
nonsteroidal anti-inflammatory drug (NSAID) used in
veterinary medicine for the relief of pain and inflammation in cats and dogs.
[1]
[2] It is a
COX-2 inhibitor (coxib ).
References
^ Gaynor JS, Muir WM (2014). "Robenacoxib". Handbook of Veterinary Pain Management (3rd, revised ed.). Elsevier Health Sciences.
ISBN
9780323222143 .
^ Clark-Price S (2014). "Nonsteroidal anti-inflammatory drugs and corticosteroids: Robenacoxib". In Egger CM, Love L, Doherty T (eds.). Pain management in veterinary practice . Ames, Iowa: Wiley-Blackwell.
ISBN
9781118761601 .
External links
"Robenacoxib" . Drug Information Portal . U.S. National Library of Medicine.
Receptor (
ligands )
DP (D2 ) Tooltip Prostaglandin D2 receptor
DP1 Tooltip Prostaglandin D2 receptor 1
DP2 Tooltip Prostaglandin D2 receptor 2
EP (E2 ) Tooltip Prostaglandin E2 receptor
EP1 Tooltip Prostaglandin EP1 receptor
EP2 Tooltip Prostaglandin EP2 receptor
EP3 Tooltip Prostaglandin EP3 receptor
EP4 Tooltip Prostaglandin EP4 receptor Unsorted
FP (F2α ) Tooltip Prostaglandin F receptor
IP (I2 ) Tooltip Prostacyclin receptor
TP (TXA2 ) Tooltip Thromboxane receptor Unsorted
Enzyme (
inhibitors )
COX (
PTGS )
PGD2 S Tooltip Prostaglandin D synthase
PGES Tooltip Prostaglandin E synthase
PGFS Tooltip Prostaglandin F synthase
PGI2 S Tooltip Prostacyclin synthase
TXAS Tooltip Thromboxane A synthase
Others