Isoxicam is a
nonsteroidal anti-inflammatory drug (NSAID) that was taken or applied to reduce
inflammation and as an
analgesic reducing pain in certain conditions. The drug was introduced in 1983 by the
Warner-Lambert Company. Isoxicam is a chemical analog of
piroxicam (Feldene) which has a pyridine ring in lieu of an isoxazole ring. In 1985 isoxicam was withdrawn from the French market, due to adverse effects, namely
toxic epidermal necrolysis resulting in death. Although these serious side effects were observed only in France, the drug was withdrawn worldwide.[1][2]
References
^Consolidated List of products whose consumption and/or sale have been banned, withdrawn, severely restricted or not approved by Governments, United Nations, 2003, p. 123
link to 2005 ed