There is some, albeit mixed, in vitro evidence that the
antidepressant and modestly selective DRI
amineptine may in addition to inhibiting the reuptake of dopamine selectively induce the presynaptic release of dopamine without affecting that of
norepinephrine or
serotonin.[3][4][5]
^Bonnet JJ, Benmansour S, Costentin J, Parker EM, Cubeddu LX (June 1990). "Thermodynamic analyses of the binding of substrates and uptake inhibitors on the neuronal carrier of dopamine labeled with [3H]GBR 12783 or [3H]mazindol". The Journal of Pharmacology and Experimental Therapeutics. 253 (3): 1206–14.
PMID2141637.
^Bonnet JJ, Chagraoui A, Protais P, Costentin J (1987). "Interactions of amineptine with the neuronal dopamine uptake system: Neurochemicalin vitro and in vivo studies". Journal of Neural Transmission. 69 (3–4): 211–220.
doi:
10.1007/BF01244342.
ISSN0300-9564.
PMID3625193.
S2CID9886698.
† References for all endogenous human TAAR1 ligands are provided at
List of trace amines
‡ References for synthetic TAAR1 agonists can be found at
TAAR1 or in the associated compound articles. For TAAR2 and TAAR5 agonists and inverse agonists, see
TAAR for references.