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Chemical compound
This article is about a non-clinically used progestin compound. For the pharmaceutical drug, see
chlormadinone acetate .
Chlormadinone
Other names Chlordione; 17α-Hydroxy-6-chloro-6-dehydroprogesterone; 17α-Hydroxy-6-chloropregna-4,6-diene-3,20-dione; 6-Chloro-17α-hydroxypregna-4,6-diene-3,20-dione
ATC code
(8R ,9S ,10R ,13S ,14S ,17R )-17-acetyl-6-chloro-17-hydroxy-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H -cyclopenta[a ]phenanthren-3-one
CAS Number
PubChem
CID
ChemSpider
UNII
CompTox Dashboard (
EPA )
ECHA InfoCard
100.016.185
Formula C 21 H 27 Cl O 3
Molar mass 362.89 g·mol−1 3D model (
JSmol )
O=C4\C=C3\C(\Cl)=C/[C@@H]1[C@H](CC[C@@]2([C@@](O)(C(=O)C)CC[C@@H]12)C)[C@@]3(C)CC4
InChI=1S/C21H27ClO3/c1-12(23)21(25)9-6-16-14-11-18(22)17-10-13(24)4-7-19(17,2)15(14)5-8-20(16,21)3/h10-11,14-16,25H,4-9H2,1-3H3/t14-,15+,16+,19-,20+,21+/m1/s1
Key:VUHJZBBCZGVNDZ-TTYLFXKOSA-N
Chlormadinone is a
progestin which was never marketed.
[1]
[2] An
acylated derivative,
chlormadinone acetate , is used clinically as a
pharmaceutical
drug .
[1]
[2]
It was patented in 1958 and approved for medical use in 1963.
[3] While chlormadinone is sometimes used as a synonym for chlormadinone acetate , what is almost always being referred to is chlormadinone acetate and not chlormadinone.
See also
References
PR Tooltip Progesterone receptor
Agonists
Testosterone derivatives: Progestins:
6,6-Difluoronorethisterone
6,6-Difluoronorethisterone acetate
17α-Allyl-19-nortestosterone
Allylestrenol
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RU-2309
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Trendione
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Mixed (
SPRMs Tooltip Selective progesterone receptor modulators ) Antagonists
mPR Tooltip Membrane progesterone receptor (
PAQR Tooltip Progestin and adipoQ receptor )