SoRI-9409 is a mixed
mu opioid receptorpartial agonist and
delta opioid receptorantagonist, used in biomedical research. It produces moderate analgesic effects without development of tolerance and with reduced withdrawal symptoms compared to standard opioid analgesics,[1] as well as showing anti-addictive effects that may be useful in the treatment of
alcoholism.[2][3]
References
^Wells JL, Bartlett JL, Ananthan S, Bilsky EJ (May 2001). "In vivo pharmacological characterization of SoRI 9409, a nonpeptidic opioid mu-agonist/delta-antagonist that produces limited antinociceptive tolerance and attenuates morphine physical dependence". The Journal of Pharmacology and Experimental Therapeutics. 297 (2): 597–605.
PMID11303048.