Gamma-aminobutyric acid receptor subunit alpha-1 is a
protein that in humans is encoded by the GABRA1gene.[5]
GABA is the major
inhibitory neurotransmitter in the
mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.[6]
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^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
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