French microbiologist, biochemist and Nobel laureate
Emmanuelle Marie Charpentier (French:
[ɛmanɥɛl ʃaʁpɑ̃tje] ; born 11 December 1968
[2] ) is a French professor and researcher in
microbiology ,
genetics , and
biochemistry .
[1] As of 2015, she has been a director at the
Max Planck Institute for Infection Biology in
Berlin . In 2018, she founded an independent
research institute , the Max Planck Unit for the Science of Pathogens.
[3] In 2020, Charpentier and American biochemist
Jennifer Doudna of the
University of California, Berkeley , were awarded the
Nobel Prize in Chemistry "for the development of a method for
genome editing " (through
CRISPR ). This was the first science Nobel Prize ever won by two women only.
[4]
[5]
[6]
Early life and education
Born in 1968 in
Juvisy-sur-Orge in France, Charpentier studied biochemistry, microbiology, and genetics at the
Pierre and Marie Curie University (which became the Faculty of Science of
Sorbonne University ) in Paris.
[7] She was a graduate student at the
Institut Pasteur from 1992 to 1995 and was awarded a research doctorate. Charpentier's PhD work investigated molecular mechanisms involved in
antibiotic resistance .
[8] Her paternal grandfather was an
Armenian who escaped to France during the
Armenian genocide and met his wife in
Marseille .
[9]
Career and research
The
Max Planck Institute for Infection Biology in Berlin, Germany
Charpentier worked as a university teaching assistant at Pierre and Marie Curie University from 1993 to 1995 and as a postdoctoral fellow at the
Institut Pasteur from 1995 to 1996. She moved to the US and worked as a postdoctoral fellow at
Rockefeller University in New York from 1996 to 1997. During this time, Charpentier worked in the lab of microbiologist
Elaine Tuomanen .
[10] Tuomanen's lab investigated how the pathogen
Streptococcus pneumoniae utilizes mobile genetic elements to alter its genome. Charpentier also helped to demonstrate how S. pneumoniae develops
vancomycin resistance.
[11]
Charpentier worked as an assistant research scientist at the
New York University Medical Center from 1997 to 1999. There she worked in the lab of Pamela Cowin, a skin-cell biologist interested in mammalian gene manipulation. Charpentier published a paper exploring the regulation of hair growth in mice.
[12] She held the position of Research Associate at the
St. Jude Children's Research Hospital and at the
Skirball Institute of Biomolecular Medicine
[13] in New York from 1999 to 2002.
[7]
After five years in the United States, Charpentier returned to Europe and became the lab head and a guest professor at the Institute of Microbiology and Genetics,
University of Vienna , from 2002 to 2004. In 2004, Charpentier published her discovery of an RNA molecule involved in the regulation of virulence-factor synthesis in
Streptococcus pyogenes .
[14] From 2004 to 2006 she was lab head and an assistant professor at the Department of Microbiology and Immunobiology. In 2006 she became a
privatdozentin (Microbiology) and received her
habilitation at the Centre of Molecular Biology. From 2006 to 2009 she worked as lab head and associate professor at the
Max F. Perutz Laboratories .
[7]
Charpentier moved to Sweden and became lab head and associate professor at the Laboratory for
Molecular Infection Medicine Sweden (MIMS), at
Umeå University . She held the position of group leader from 2008 to 2013 and was visiting professor from 2014 to 2017.
[15] She moved to Germany to act as department head and W3 Professor at the
Helmholtz Centre for Infection Research
[16] in Braunschweig and the
Hannover Medical School from 2013 until 2015. In 2014 she became an
Alexander von Humboldt Professor .
[7]
In 2015 Charpentier accepted an offer from the German
Max Planck Society to become a scientific member of the society and a director at the
Max Planck Institute for Infection Biology in
Berlin . Since 2016, she has been an Honorary Professor at
Humboldt University in Berlin; since 2018, she is the Founding and acting director of the
Max Planck Unit for the Science of Pathogens .
[7]
[17]
[18] Charpentier retained her position as visiting professor at Umeå University until the end of 2017 when a new donation from the Kempe Foundations and the
Knut and Alice Wallenberg Foundation allowed her to offer more young researchers positions within research groups of the MIMS Laboratory.
[19]
CRISPR/Cas9
Charpentier is best known for her Nobel-winning work of deciphering the molecular mechanisms of a bacterial immune system, called
CRISPR /
Cas9 , and repurposing it into a tool for
genome editing . In particular, she uncovered a novel mechanism for the maturation of a non-coding RNA which is pivotal in the function of CRISPR/Cas9. Specifically, Charpentier demonstrated that a small RNA called
tracrRNA is essential for the maturation of crRNA.
[20]
In 2011, Charpentier met
Jennifer Doudna at a research conference in San Juan, Puerto Rico, and they began a collaboration.
[10] Working with Doudna's laboratory, Charpentier's laboratory showed that Cas9 could be used to make cuts in any
DNA sequence desired.
[21]
[22] The method they developed involved the combination of Cas9 with easily created synthetic "guide RNA" molecules. Synthetic guide RNA is a chimera of crRNA and tracrRNA; therefore, this discovery demonstrated that the CRISPR-Cas9 technology could be used to edit the genome with relative ease.
[22] Researchers worldwide have employed this method successfully to edit the DNA sequences of plants, animals, and laboratory
cell lines . Since its discovery, CRISPR has revolutionized genetics by allowing scientists to edit genes to probe their role in health and disease and to develop genetic therapies with the hope that it will prove safer and more effective than the first generation of gene therapies.
[6]
In 2013, Charpentier co-founded
CRISPR Therapeutics and ERS Genomics along with Shaun Foy and Rodger Novak.
[23]
Awards
Emmanuelle Charpentier in the Senate Chamber of York University in 2016, after giving her Gairdner Foundation International Award Lecture
In 2015,
Time magazine designated Charpentier one of the
Time 100 most influential people in the world (together with Jennifer Doudna).
[24]
[25]
Charpentier's awards are:
Nobel Prize in Chemistry ,
[26] the
Breakthrough Prize in
Life Sciences , the
Louis-Jeantet Prize for Medicine , the
Gruber Foundation International Prize in Genetics, the
Leibniz Prize , the
Tang Prize , the
Japan Prize , and the
Kavli Prize in Nanoscience. She has won the
BBVA Foundation Frontiers of Knowledge Award jointly with
Jennifer Doudna and
Francisco Mojica .
[27]
Honorary doctorate degrees
Memberships
In popular culture
In 2019, Charpentier was a featured character in the play STEM FEMMES by Philadelphia theater company Applied Mechanics.
[86]
In 2021,
Walter Isaacson detailed the story of Jennifer Doudna and her collaboration with Charpentier leading to the discovery of CRISPR/CAS-9, in the biography
The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race .
[87]
References
^
a
b Abbott, Alison (2016).
"The quiet revolutionary: How the co-discovery of CRISPR explosively changed Emmanuelle Charpentier's life" . Nature . 532 (7600): 432–434.
Bibcode :
2016Natur.532..432A .
doi :
10.1038/532432a .
PMID
27121823 .
^
"The Nobel Prize in Chemistry 2020" . NobelPrize.org . Retrieved 7 October 2020 .
^
"CRISPR discoverer gets own research institute" . 19 April 2017. Retrieved 14 December 2018 .
^
a
b
"Press release: The Nobel Prize in Chemistry 2020" . Nobel Foundation. Retrieved 7 October 2020 .
^ Wu, Katherine J.; Peltier, Elian (7 October 2020).
"Nobel Prize in Chemistry Awarded to 2 Scientists for Work on Genome Editing – Emmanuelle Charpentier and Jennifer A. Doudna developed the Crispr tool, which can alter the DNA of animals, plants and microorganisms with high precision" .
The New York Times . Retrieved 7 October 2020 .
^
a
b
"Two female CRISPR scientists make history, winning Nobel in chemistry" . STAT . 7 October 2020. Retrieved 12 October 2020 .
^
a
b
c
d
e
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^ Deffke, Uta (7 February 2017).
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^
"Nobel laureate Emmanuelle Marie Charpentier reveals Armenian identity" .
Public Radio of Armenia . 6 September 2022. Archived from
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^
a
b Abbott, Alison (28 April 2016).
"The quiet revolutionary: How the co-discovery of CRISPR explosively changed Emmanuelle Charpentier's life" . Nature News . 532 (7600): 432–434.
Bibcode :
2016Natur.532..432A .
doi :
10.1038/532432a .
PMID
27121823 .
^ Novak, R.; Henriques, B.; Charpentier, E.; Normark, S.; Tuomanen, E. (1999).
"Emergence of vancomycin tolerance in Streptococcus pneumoniae" . Nature . 399 (6736): 590–593.
Bibcode :
1999Natur.399..590N .
doi :
10.1038/21202 .
ISSN
1476-4687 .
PMID
10376600 .
S2CID
424755 .
^ Charpentier, Emmanuelle; Lavker, Robert M.; Acquista, Elizabeth; Cowin, Pamela (17 April 2000).
"Plakoglobin Suppresses Epithelial Proliferation and Hair Growth in Vivo" . Journal of Cell Biology . 149 (2): 503–520.
doi :
10.1083/jcb.149.2.503 .
ISSN
0021-9525 .
PMC
2175163 .
PMID
10769039 .
^
"Skirball Institute of Biomolecular Medicine" . NYU Langone Health .
^ Mangold, Monika; Siller, Maria; Roppenser, Bernhard; Vlaminckx, Bart J. M.; Penfound, Tom A.; Klein, Reinhard; Novak, Rodger; Novick, Richard P.; Charpentier, Emmanuelle (2004). "Synthesis of group A streptococcal virulence factors is controlled by a regulatory RNA molecule". Molecular Microbiology . 53 (5): 1515–1527.
doi :
10.1111/j.1365-2958.2004.04222.x .
ISSN
1365-2958 .
PMID
15387826 .
S2CID
34811329 .
^
"Research Groups" . MIMS . Retrieved 10 October 2020 .
^
"Home" . Helmholtz Centre for Infection Research .
^
"Emmanuelle Charpentier, CRISPR-Cas9, Max Planck Institute for Infection Biology" . Max Planck Unit for the Science of Pathogens .
^
CRISPR discoverer get own research institute Retrieved 4 September 2018
^
"Emmanuelle Charpentier – Regulation in Infection Biology – Funding" . Molecular Infection Medicine Sweden (MIMS). Archived from
the original on 4 March 2016. Retrieved 3 January 2016 .
^ Deltcheva, Elitza; Chylinski, Krzysztof; Sharma, Cynthia M.; Gonzales, Karine; Chao, Yanjie; Pirzada, Zaid A.; Eckert, Maria R.; Vogel, Jörg; Charpentier, Emmanuelle (March 2011).
"CRISPR RNA maturation by trans -encoded small RNA and host factor RNase III" . Nature . 471 (7340): 602–607.
Bibcode :
2011Natur.471..602D .
doi :
10.1038/nature09886 .
ISSN
1476-4687 .
PMC
3070239 .
PMID
21455174 .
^
"CRISPR Therapeutics, About us" . Archived from
the original on 29 June 2015. Retrieved 15 June 2015 .
^
a
b Jinek, Martin; Chylinski, Krzysztof; Fonfara, Ines; Hauer, Michael; Doudna, Jennifer A.; Charpentier, Emmanuelle (17 August 2012).
"A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity" . Science . 337 (6096): 816–821.
Bibcode :
2012Sci...337..816J .
doi :
10.1126/science.1225829 .
ISSN
0036-8075 .
PMC
6286148 .
PMID
22745249 .
^ Cohen, Jon (15 February 2017).
"How the battle lines over CRISPR were drawn" . Science | AAAS . Retrieved 10 June 2020 .
^ King, Mary-Claire (16 April 2015).
"Emmanuelle Charpentier & Jennifer Doudna" .
Time . Retrieved 30 August 2022 .
^
"Emmanuelle Charpentier named in Time magazine's '100 most influential people in world' list" . Umeå University. 13 April 2015. Archived from
the original on 11 August 2018. Retrieved 15 June 2015 .
^
"The Nobel Prize in Chemistry 2020" . NobelPrize.org . Retrieved 10 August 2022 .
^
"Emmanuelle Charpentier – Frontiers of Knowledge Laureate" . BBVA . Retrieved 10 September 2022 .
^ Wien, Arbeiterkammer (4 May 2020).
"Theodor Körner Fonds > 2009 > Ausgezeichnete Arbeiten" . www.theodorkoernerfonds.at . Archived from
the original on 3 October 2017. Retrieved 3 October 2017 .
^
"Eric K. Fernström's Prize to Emmanuelle Charpentier" . Molecular Infection Medicine Sweden. 9 June 2011. Retrieved 15 June 2015 .
^
"Alexander von Humboldt sponsorship" . Humboldt Foundation. Archived from
the original on 16 August 2017. Retrieved 15 August 2017 .
^
"Göran Gustafsson Prize for Emmanuelle Charpentier" . Molecular Infection Medicine Sweden. Retrieved 15 June 2015 .
^
"MIMS group leader Emmanuelle Charpentier receives Dr. Paul Janssen Award for discoveries of CRISPR-Cas9" . Molecular Infection Medicine Sweden. Retrieved 15 June 2015 .
^
"Emmanuelle Charpentier receives Jacob Heskel Gabbay Award" . Umeå University. Archived from
the original on 25 August 2017. Retrieved 15 June 2015 .
^ Mary-Claire King (15 April 2015).
"Emmanuelle Charpentier & Jennifer Doudna" . Time . Archived from
the original on 9 August 2018. Retrieved 17 April 2015 .
^
"Umeå University, press release: Emmanuelle Charpentier honored with Breakthrough Prize in Life Sciences" . Umeå University. 10 November 2014. Archived from
the original on 25 August 2017. Retrieved 15 June 2015 . (shared with Jennifer Doudna)
^
"Foundation Louis-Jeanet: "The 2015 Louis-Jeantet Prize-Winners" " . Retrieved 19 April 2015 .
^
"Laureates 2015 – Professor Emmanuelle Charpentier" . Jung-Stiftung für Wissenschaft und Forschung. May 2015. Archived from
the original on 25 September 2015. Retrieved 5 June 2015 .
^
"Zwei Humboldtianer erhalten Prinzessin-von-Asturien-Preise 2015" . humboldt-professur.de . Bonn: Alexander von Humboldt-Stiftung. 29 May 2015. Archived from
the original on 20 June 2020. Retrieved 18 June 2020 .
^
"YaleNews: Gruber Foundation honors excellence in neuroscience, cosmology, and genetics" . Yale University. 16 June 2015. Retrieved 17 June 2015 .
^
"Emmanuelle Charpentier receives Carus Medal" . Helmholtz Centre for Infection research. 7 September 2015. Retrieved 8 September 2015 .
^
"Massry winners helped launch gene editing revolution" . 7 October 2015. Retrieved 12 January 2018 .
^
"Winner of the 2015 Bayer Family Hansen Award" . Retrieved 15 December 2021 .
^
"MIMS – Curriculum Vitae Emmanuelle Charpentier" . www.mims.umu.se . Archived from
the original on 1 November 2015. Retrieved 12 January 2018 .
^
"France celebrates Emmanuelle Charpentier during the L'Oreal-UNESCO week in Paris" . mims.umu.se . Molecular Infection Medicine Sweden. 24 March 2016. Retrieved 20 November 2017 .
^
"Leibniz Prizes 2016: DFG Honours Ten Researchers" .
Deutsche Forschungsgemeinschaft . 10 December 2015. Archived from
the original on 30 August 2019. Retrieved 3 January 2016 .
^
"Canada Gairdner International Award" . Archived from
the original on 29 March 2016. Retrieved 25 March 2016 .
^
"Paul Ehrlich and Ludwig Darmstaedter Prize 2016" .
^
"Tang Prize – Laureates" . www.tang-prize.org . Retrieved 12 January 2018 .
^
"The 2016 HFSP Nakasone Award goes to Emmanuelle Charpentier & Jennifer Doudna" . Human Frontier Science Programme. Archived from
the original on 27 September 2018. Retrieved 9 September 2016 .
^
"Décret du 31 décembre 2015 portant promotion et nomination – Légifrance" .
^
"Die Preisträger" . meyenburg-stiftung.de . Heidelberg: Meyenburg-Stiftung. 2018. Retrieved 18 June 2020 .
^
"Wilhelm-Exner-Medaille" . www.wilhelmexner.org . Archived from
the original on 1 August 2017. Retrieved 12 January 2018 .
^
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^
"Laureates" . Premios Fronteras .
^
"The Japan Prize Foundation" . www.japanprize.jp . Retrieved 12 January 2018 .
^
"Gene Editing Pioneers Receive Americas Most Distinguished Prize in Medicine" . www.amc.edu . Retrieved 12 January 2018 .
^
"Pour le Mérite: Emmanuelle Charpentier" (PDF) . www.orden-pourlemerite.de . 2017. Archived from
the original (PDF) on 7 October 2020. Retrieved 18 June 2020 .
^
"2018 Kavli Prize in Nanoscience" . www.kavliprize.org . 22 May 2018. Retrieved 13 December 2021 .
^
"Ehrenzeichen für Geografin Leitner und Molekularbiologin Charpentier" . Der Standard .
^
"Bijvoet Medal" . Bijvoet Center for Biomolecular Research. Archived from
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^
Harvey Prize 2018
^
"2019 års Scheelepris till Emmanuelle Charpentier" . 1 February 2019. Archived from
the original on 31 July 2020. Retrieved 15 July 2019 .
^
"Artikel: Bekanntgabe vom 1. Oktober 2019" .
Der Bundespräsident (in German). Retrieved 11 February 2023 .
^
"The Wolf Prize" .
^ Bourquenoud, Sarah (1 October 2016).
"L'EPFL fête ses nouveaux diplômés" . EPFL (in French). Retrieved 2 December 2023 .
^
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the original on 3 October 2017. Retrieved 17 June 2020 .
^
"Darren Walker, Ford Foundation President, to Speak at NYU's Commencement" . nyu.edu .
^
"MIMS – Internationally renowned researchers become 2017 honorary doctors at the Faculty of Medicine" . www.mims.umu.se .
^
"Charpentier: Be open to new perspectives" . westernu.ca . 25 October 2017.
^
HKUST Holds 25th Congregation Conferring Honorary Doctorates on Four Distinguished Academics and Community Leaders , retrieved 20 November 2017
^
"Doctor honoris causa and ISV 20th anniversary" . Archived from
the original on 23 April 2018. Retrieved 23 April 2018 .
^
"Darwin hosts Professor Emmanuelle Charpentier | www.darwin.cam.ac.uk" . www.darwin.cam.ac.uk . Archived from
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^
"Businessman, scientists, actor and architect honoured as University marks its Foundation Day" . manchester.ac.uk .
^
"McGill's Honorary Degree recipients for Spring Convocation 2019" . mcgill.ca . Montreal: McGill University. 16 April 2019. Retrieved 18 June 2020 .
^
"Find people in the EMBO Communities" . Find people in the EMBO Communities . Retrieved 2 December 2023 .
^
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^
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^
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^
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^
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^
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^
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^
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^
"News" . European Academy of Sciences and Arts . Retrieved 7 October 2020 .
^ Dulle, Colleen (13 August 2021).
"Pope Francis appointed three women to the Pontifical Academy of Sciences this summer. What's their role at the Vatican?" .
America . Retrieved 15 October 2021 .
^ Reinckens, Mina.
" 'STEM FEMMES' centers women in science with theater" . Broad Street Review . Retrieved 24 February 2021 . [
permanent dead link ]
^ Isaacson, Walter (2021).
The code breaker : Jennifer Doudna, gene editing, and the future of the human race (First hardcover ed.). New York: Simon & Schuster.
ISBN
978-1-9821-1585-2 .
OCLC
1187220557 .
External links
Fields, disciplines Theories, concepts Related
Awards for Emmanuelle Charpentier
1901–1925 1926–1950 1951–1975 1976–2000 2001–present
Mathematics
Fundamental physics
Nima Arkani-Hamed ,
Alan Guth ,
Alexei Kitaev ,
Maxim Kontsevich ,
Andrei Linde ,
Juan Maldacena ,
Nathan Seiberg ,
Ashoke Sen ,
Edward Witten (2012)
Special :
Stephen Hawking ,
Peter Jenni ,
Fabiola Gianotti (ATLAS),
Michel Della Negra ,
Tejinder Virdee ,
Guido Tonelli ,
Joseph Incandela (CMS) and
Lyn Evans (LHC) (2013)
Alexander Polyakov (2013)
Michael Green and
John Henry Schwarz (2014)
Saul Perlmutter and members of the
Supernova Cosmology Project ;
Brian Schmidt ,
Adam Riess and members of the
High-Z Supernova Team (2015)
Special :
Ronald Drever ,
Kip Thorne ,
Rainer Weiss and contributors to
LIGO project (2016)
Yifang Wang ,
Kam-Biu Luk and the
Daya Bay team ,
Atsuto Suzuki and the
KamLAND team,
Kōichirō Nishikawa and the
K2K /
T2K team,
Arthur B. McDonald and the
Sudbury Neutrino Observatory team,
Takaaki Kajita and
Yōichirō Suzuki and the
Super-Kamiokande team (2016)
Joseph Polchinski ,
Andrew Strominger ,
Cumrun Vafa (2017)
Charles L. Bennett ,
Gary Hinshaw ,
Norman Jarosik ,
Lyman Page Jr. ,
David Spergel (2018)
Special :
Jocelyn Bell Burnell (2018)
Charles Kane and
Eugene Mele (2019)
Special :
Sergio Ferrara ,
Daniel Z. Freedman ,
Peter van Nieuwenhuizen (2019)
The Event Horizon Telescope Collaboration (2020)
Eric Adelberger ,
Jens H. Gundlach and
Blayne Heckel (2021)
Special :
Steven Weinberg (2021)
Hidetoshi Katori and
Jun Ye (2022)
Charles H. Bennett ,
Gilles Brassard ,
David Deutsch ,
Peter W. Shor (2023)
John Cardy and
Alexander Zamolodchikov (2024)
Life sciences
Cornelia Bargmann ,
David Botstein ,
Lewis C. Cantley ,
Hans Clevers ,
Titia de Lange ,
Napoleone Ferrara ,
Eric Lander ,
Charles Sawyers ,
Robert Weinberg ,
Shinya Yamanaka and
Bert Vogelstein (2013)
James P. Allison ,
Mahlon DeLong ,
Michael N. Hall ,
Robert S. Langer ,
Richard P. Lifton and
Alexander Varshavsky (2014)
Alim Louis Benabid ,
Charles David Allis ,
Victor Ambros ,
Gary Ruvkun ,
Jennifer Doudna and
Emmanuelle Charpentier (2015)
Edward Boyden ,
Karl Deisseroth ,
John Hardy ,
Helen Hobbs and
Svante Pääbo (2016)
Stephen J. Elledge ,
Harry F. Noller ,
Roeland Nusse ,
Yoshinori Ohsumi ,
Huda Zoghbi (2017)
Joanne Chory ,
Peter Walter ,
Kazutoshi Mori ,
Kim Nasmyth ,
Don W. Cleveland (2018)
C. Frank Bennett and
Adrian R. Krainer ,
Angelika Amon ,
Xiaowei Zhuang ,
Zhijian Chen (2019)
Jeffrey M. Friedman ,
Franz-Ulrich Hartl ,
Arthur L. Horwich ,
David Julius ,
Virginia Man-Yee Lee (2020)
David Baker ,
Catherine Dulac ,
Dennis Lo ,
Richard J. Youle [
de ] (2021)
Jeffery W. Kelly ,
Katalin Karikó ,
Drew Weissman ,
Shankar Balasubramanian ,
David Klenerman and
Pascal Mayer (2022)
Clifford P. Brangwynne ,
Anthony A. Hyman ,
Demis Hassabis ,
John Jumper ,
Emmanuel Mignot ,
Masashi Yanagisawa (2023)
Carl June ,
Michel Sadelain ,
Sabine Hadida ,
Paul Negulescu ,
Fredrick Van Goor ,
Thomas Gasser ,
Ellen Sidransky and
Andrew Singleton (2024)
Astrophysics
Maarten Schmidt ,
Donald Lynden-Bell (2008)
Jerry E. Nelson ,
Raymond N. Wilson ,
Roger Angel (2010)
David C. Jewitt ,
Jane Luu ,
Michael E. Brown (2012)
Alan Guth ,
Andrei Linde ,
Alexei Starobinsky (2014)
Ronald Drever ,
Kip Thorne ,
Rainer Weiss (2016)
Ewine van Dishoeck (2018)
Andrew Fabian (2020)
Roger Ulrich ,
Jørgen Christensen-Dalsgaard ,
Conny Aerts (2022)
Nanoscience
Louis E. Brus ,
Sumio Iijima (2008)
Donald Eigler ,
Nadrian Seeman (2010)
Mildred Dresselhaus (2012)
Thomas Ebbesen ,
Stefan Hell ,
John Pendry (2014)
Gerd Binnig ,
Christoph Gerber ,
Calvin Quate (2016)
Emmanuelle Charpentier ,
Jennifer Doudna ,
Virginijus Šikšnys (2018)
Harald Rose ,
Maximilian Haider ,
Knut Urban ,
Ondrej Krivanek (2020)
Jacob Sagiv ,
Ralph G. Nuzzo ,
David L. Allara ,
George M. Whitesides (2022)
Neuroscience
Sten Grillner ,
Thomas Jessell ,
Pasko Rakic (2008)
Richard Scheller ,
Thomas C. Südhof ,
James Rothman (2010)
Cornelia Bargmann ,
Winfried Denk ,
Ann Graybiel (2012)
Brenda Milner ,
John O'Keefe ,
Marcus Raichle (2014)
Eve Marder ,
Michael Merzenich ,
Carla J. Shatz (2016)
A. James Hudspeth ,
Robert Fettiplace ,
Christine Petit (2018)
David Julius ,
Ardem Patapoutian (2020)
Jean-Louis Mandel ,
Harry T. Orr ,
Christopher A. Walsh ,
Huda Zoghbi (2022)
Prince of Asturias Award for Technical and Scientific Research
1981:
Alberto Sols
1982:
Manuel Ballester
1983:
Luis Antonio Santaló Sors
1984:
Antonio Garcia-Bellido
1985:
David Vázquez Martínez and
Emilio Rosenblueth
1986:
Antonio González González
1987:
Jacinto Convit and
Pablo Rudomín
1988:
Manuel Cardona and
Marcos Moshinsky
1989:
Guido Münch
1990:
Santiago Grisolía and
Salvador Moncada
1991:
Francisco Bolívar Zapata
1992:
Federico García Moliner
1993:
Amable Liñán
1994:
Manuel Patarroyo
1995:
Manuel Losada Villasante and
Instituto Nacional de Biodiversidad of Costa Rica
1996:
Valentín Fuster
1997:
Atapuerca research team
1998:
Emilio Méndez Pérez and
Pedro Miguel Echenique Landiríbar
1999:
Ricardo Miledi and
Enrique Moreno González
2000:
Robert Gallo and
Luc Montagnier
2001:
Craig Venter ,
John Sulston ,
Francis Collins ,
Hamilton Smith and
Jean Weissenbach
2002:
Lawrence Roberts ,
Robert E. Kahn ,
Vinton Cerf and
Tim Berners-Lee
2003:
Jane Goodall
2004:
Judah Folkman ,
Tony Hunter ,
Joan Massagué ,
Bert Vogelstein and
Robert Weinberg
2005:
Antonio Damasio
2006:
Juan Ignacio Cirac
2007:
Peter Lawrence and
Ginés Morata
2008:
Sumio Iijima ,
Shuji Nakamura ,
Robert Langer ,
George M. Whitesides and
Tobin Marks
2009:
Martin Cooper and
Raymond Tomlinson
2010:
David Julius ,
Baruch Minke and
Linda Watkins
2011:
Joseph Altman ,
Arturo Álvarez-Buylla and
Giacomo Rizzolatti
2012:
Gregory Winter and
Richard A. Lerner
2013:
Peter Higgs ,
François Englert and
European Organization for Nuclear Research CERN
2014:
Avelino Corma Canós ,
Mark E. Davis and
Galen D. Stucky
Princess of Asturias Award for Technical and Scientific Research
2015:
Emmanuelle Charpentier and
Jennifer Doudna
2016:
Hugh Herr
2017:
Rainer Weiss ,
Kip S. Thorne ,
Barry C. Barish and the
LIGO Scientific Collaboration
2018:
Svante Pääbo
2019:
Joanne Chory and
Sandra Myrna Díaz
2020:
Yves Meyer ,
Ingrid Daubechies ,
Terence Tao and
Emmanuel Candès
2021:
Katalin Karikó ,
Drew Weissman ,
Philip Felgner ,
Uğur Şahin ,
Özlem Türeci ,
Derrick Rossi and
Sarah Gilbert
2022:
Geoffrey Hinton ,
Yann LeCun ,
Yoshua Bengio and
Demis Hassabis
2023:
Jeffrey I. Gordon ,
Everett Peter Greenberg and
Bonnie Bassler
1970s 1980s 1990s 2000s 2010s 2020s
Sustainable Development Biopharmaceutical Science Sinology Rule of Law
International National Academics Other