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Computational biologist
John Michael Jumper is an American senior research scientist at
DeepMind Technologies.
[4]
[5]
[6] Jumper and his colleagues created
AlphaFold ,
[7] an
artificial intelligence (AI) model to predict
protein structures from their
amino acid sequence with high accuracy.
[8] Jumper has stated that the AlphaFold team plans to release 100 million protein structures.
[9] The scientific journal
Nature included Jumper as one of the ten "people who mattered" in science in their annual listing of
Nature's 10 in 2021.
[8]
[3]
Education
Jumper was educated at the
University of Chicago where he was awarded a
PhD in 2017 for research on using machine learning to simulate
protein folding and dynamics, being co-supervised by Tobin R Sosnick and
Karl Freed .
[1] Jumper also studied physics at the
University of Cambridge , where he was on the
Marshall Scholarship ,
[10] and holds a
Bachelor of Science degree in Physics and Mathematics from
Vanderbilt University .
[2]
Career and research
Jumper's research investigates algorithms for
protein structure prediction .
[4]
AlphaFold
This image represents the final product of AlphaFold and it compares its results with other competitors at the CASP competition.
AlphaFold
[7]
[11] is a
deep learning algorithm developed by Jumper and his team at DeepMind, a research lab acquired by Google's parent company
Alphabet Inc . It is an artificial intelligence program which performs
predictions of protein structure .
[12]
Awards and honours
In November 2020, AlphaFold was named the winner of the
Critical Assessment of Structure Prediction (CASP) competition. This international competition benchmarks algorithms to determine which one can best predict the 3D structure of proteins. AlphaFold won the competition, out performing other algorithms and making it the first machine learning algorithm to be able to accurately predict the 3D
structure of proteins .
In 2021 Jumper was awarded the
BBVA Foundation Frontiers of Knowledge Award in the category "Biology and Biomedicine".
[13] In 2022 Jumper received the
Wiley Prize in Biomedical Sciences
[14] and for 2023 the
Breakthrough Prize in Life Sciences for developing AlphaFold, which accurately predicts the structure of a protein.
[15] In 2023 he was awarded the
Canada Gairdner International Award
[16] and the
Albert Lasker Award for Basic Medical Research .
[17]
References
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