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French–American biologist
Catherine Dulac is a French–American biologist.
[2] She is the Higgins Professor in Molecular and Cellular Biology at Harvard University, where she served as department chair from 2007 to 2013.
[3] She is also an investigator at the Howard Hughes Medical Institute. She was born in 1963 in France. She came to the United States for her postdoctoral study in 1991.
Dulac has done extensive research on the molecular biology of
olfactory signaling in
mammals , particularly including
pheromones ,
[4] and downstream
brain circuits controlling sex-specific behaviors.
[5] She developed a novel screening strategy based on screening
cDNA libraries from single
neurons and a new method of cloning genes from single neurons. As a postdoc, Dulac discovered the first family of mammalian pheromone receptors when working in Nobel laureate
Richard Axel 's laboratory at Columbia University.
[6]
Biography
Dulac grew up in
Montpellier, France , graduated from the École Normale Supérieure de la rue d'Ulm, Paris, and earned a Ph.D. in
developmental biology from the
University of Paris in 1991.
[1] She worked with
Nicole Le Douarin on developmental biology, and carried out her postdoc studies with
Richard Axel at
Columbia University where she identified the first genes encoding mammalian pheromone receptors.
Dulac joined the faculty of
Harvard Molecular and Cell Biology in 1996,
[7] She was promoted to associate professor in 2000 and full professor in 2001. She is currently an investigator at the
Howard Hughes Medical Institute and was the Chair of Harvard's Department of Molecular and Cellular Biology
[1] until 2013. She teaches three graduate level course including Molecular Basis of Behavior, Molecular and Cellular Biology of the Senses and Their Disorders, and Molecular and Developmental Biology Neurobiology.
Publications
Notable papers
Wu, Zheng; Autry, Anita E.; Bergan, Joseph F.; Watabe-Uchida, Mitsuko; Dulac, Catherine G. (2014).
"Galanin neurons in the medial preoptic area govern parental behaviour" . Nature . 509 (7500). Springer Science and Business Media LLC: 325–330.
Bibcode :
2014Natur.509..325W .
doi :
10.1038/nature13307 .
ISSN
0028-0836 .
PMC
4105201 .
PMID
24828191 .
Bergan, Joseph F; Ben-Shaul, Yoram; Dulac, Catherine (June 3, 2014).
"Sex-specific processing of social cues in the medial amygdala" . eLife . 3 . eLife Sciences Publications, Ltd: e02743.
doi :
10.7554/elife.02743 .
ISSN
2050-084X .
PMC
4038839 .
PMID
24894465 .
Gregg, C.; Zhang, J.; Butler, J. E.; Haig, D.; Dulac, C. (July 8, 2010).
"Sex-Specific Parent-of-Origin Allelic Expression in the Mouse Brain" . Science . 329 (5992). American Association for the Advancement of Science (AAAS): 682–685.
Bibcode :
2010Sci...329..682G .
doi :
10.1126/science.1190831 .
ISSN
0036-8075 .
PMC
2997643 .
PMID
20616234 .
Kimchi, Tali; Xu, Jennings; Dulac, Catherine (2007). "A functional circuit underlying male sexual behaviour in the female mouse brain". Nature . 448 (7157). Springer Science and Business Media LLC: 1009–1014.
Bibcode :
2007Natur.448.1009K .
doi :
10.1038/nature06089 .
ISSN
0028-0836 .
PMID
17676034 .
S2CID
4427883 .
Tietjen, Ian; Rihel, Jason M.; Cao, Yanxiang; Koentges, Georgy; Zakhary, Lisa; Dulac, Catherine (2003).
"Single-Cell Transcriptional Analysis of Neuronal Progenitors" . Neuron . 38 (2). Elsevier BV: 161–175.
doi :
10.1016/s0896-6273(03)00229-0 .
ISSN
0896-6273 .
PMID
12718852 .
S2CID
5872628 .
Pantages, Erica; Dulac, Catherine (2000).
"A Novel Family of Candidate Pheromone Receptors in Mammals" . Neuron . 28 (3). Elsevier BV: 835–845.
doi :
10.1016/s0896-6273(00)00157-4 .
ISSN
0896-6273 .
PMID
11163270 .
S2CID
15023062 .
Liman, E. R.; Corey, D. P.; Dulac, C. (May 11, 1999).
"TRP2: A candidate transduction channel for mammalian pheromone sensory signaling" . Proceedings of the National Academy of Sciences . 96 (10): 5791–5796.
Bibcode :
1999PNAS...96.5791L .
doi :
10.1073/pnas.96.10.5791 .
ISSN
0027-8424 .
PMC
21939 .
PMID
10318963 .
Belluscio, Leonardo; Koentges, Georgy; Axel, Richard; Dulac, Catherine (1999).
"A Map of Pheromone Receptor Activation in the Mammalian Brain" . Cell . 97 (2). Elsevier BV: 209–220.
doi :
10.1016/s0092-8674(00)80731-x .
ISSN
0092-8674 .
PMID
10219242 .
S2CID
18385498 .
Dulac, Catherine; Axel, Richard (1995).
"A novel family of genes encoding putative pheromone receptors in mammals" . Cell . 83 (2). Elsevier BV: 195–206.
doi :
10.1016/0092-8674(95)90161-2 .
ISSN
0092-8674 .
PMID
7585937 .
S2CID
18784638 .
Other
Awards and honors
She was elected a Member of the
American Philosophical Society in 2019.
[11]
References
^
a
b
c
d
e
f
g
h
[1] . academie-sciences.fr
^
"Harvard scientist Catherine Dulac awarded for work on parenting instinct" . RFI . September 14, 2020. Retrieved September 15, 2020 .
^
"McGovern Institute awards 2017 Scolnick Prize to Catherine Dulac" . MIT News . Retrieved February 3, 2018 .
^ Gitschier, J. (2011).
"Vive La Différence: An Interview with Catherine Dulac" . PLOS Genetics . 7 (6): e1002140.
doi :
10.1371/journal.pgen.1002140 .
PMC
3121755 .
PMID
21731502 .
^
"McGovern Institute awards 2017 Scolnick Prize to Catherine Dulac" . MIT News . Retrieved February 3, 2018 .
^
"Catherine Dulac" . Harvard University. Archived from
the original on June 15, 2011. Retrieved June 15, 2011 .
^
"Harvard Portrait: Catherine Dulac" , Harvard Magazine , Sept. – Oct. 2005.
^ Hastings, J. W. (May 12, 2004)
"Catherine Dulac Elected to Membership in the American Academy of Arts and Sciences"
Archived 2016-11-15 at the
Wayback Machine , Harvard University MCB News.
^
"Dulac Receives Award from Society for Neuroscience" . Harvard University – Department of Molecular & Cellular Biology . October 19, 2019. Retrieved September 10, 2020 .
^ Knapp, Alex.
"2021 Breakthrough Prize Winners Announced: Researcher Who Developed Protein Design Technology Awarded $3 Million" . Forbes . Retrieved September 10, 2020 .
^
"Catherine Dulac Elected to American Philosophical Society" . Harvard University – Department of Molecular & Cellular Biology . June 13, 2019. Retrieved September 10, 2020 .
External links
Mathematics
Fundamental physics
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