From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Pre-mRNA-processing factor 19 is a
protein that in humans is encoded by the PRPF19
gene .
[5]
[6]
In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM]
[6]
Interactions
PRPF19 has been shown to
interact with
CDC5L .
[7]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000110107 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000024735 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Mahajan KN, Mitchell BS (September 2003).
"Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase" . Proc Natl Acad Sci U S A . 100 (19): 10746–51.
Bibcode :
2003PNAS..10010746M .
doi :
10.1073/pnas.1631060100 .
PMC
196874 .
PMID
12960389 .
^
a
b
"Entrez Gene: PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)" .
^ Ajuh P, Kuster B, Panov K, Zomerdijk J C, Mann M, Lamond A I (December 2000).
"Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry" . EMBO J . 19 (23): 6569–81.
doi :
10.1093/emboj/19.23.6569 .
ISSN
0261-4189 .
PMC
305846 .
PMID
11101529 .
Further reading
Gerner C, Holzmann K, Meissner M, et al. (1999). "Reassembling proteins and chaperones in human nuclear matrix protein fractions". J. Cell. Biochem . 74 (2): 145–51.
doi :
10.1002/(SICI)1097-4644(19990801)74:2<145::AID-JCB1>3.0.CO;2-# .
PMID
10404385 .
S2CID
196598497 .
Gotzmann J, Gerner C, Meissner M, et al. (2000). "hNMP 200: a novel human common nuclear matrix protein combining structural and regulatory functions". Exp. Cell Res . 261 (1): 166–79.
doi :
10.1006/excr.2000.5025 .
PMID
11082287 .
Andersen JS, Lyon CE, Fox AH, et al. (2002).
"Directed proteomic analysis of the human nucleolus" . Curr. Biol . 12 (1): 1–11.
Bibcode :
2002CBio...12....1A .
doi :
10.1016/S0960-9822(01)00650-9 .
PMID
11790298 .
S2CID
14132033 .
Jurica MS, Licklider LJ, Gygi SR, et al. (2002).
"Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis" . RNA . 8 (4): 426–39.
doi :
10.1017/S1355838202021088 .
PMC
1370266 .
PMID
11991638 .
Scherl A, Couté Y, Déon C, et al. (2003).
"Functional proteomic analysis of human nucleolus" . Mol. Biol. Cell . 13 (11): 4100–9.
doi :
10.1091/mbc.E02-05-0271 .
PMC
133617 .
PMID
12429849 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Makarova OV, Makarov EM, Urlaub H, et al. (2004).
"A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing" . EMBO J . 23 (12): 2381–91.
doi :
10.1038/sj.emboj.7600241 .
PMC
423283 .
PMID
15175653 .
Jin J, Smith FD, Stark C, et al. (2004).
"Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization" . Curr. Biol . 14 (16): 1436–50.
Bibcode :
2004CBio...14.1436J .
doi :
10.1016/j.cub.2004.07.051 .
PMID
15324660 .
S2CID
2371325 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature . 433 (7021): 77–83.
Bibcode :
2005Natur.433...77A .
doi :
10.1038/nature03207 .
PMID
15635413 .
S2CID
4344740 .
Löscher M, Fortschegger K, Ritter G, et al. (2005).
"Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome" . Biochem. J . 388 (Pt 2): 593–603.
doi :
10.1042/BJ20041517 .
PMC
1138967 .
PMID
15660529 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8.
Bibcode :
2005Natur.437.1173R .
doi :
10.1038/nature04209 .
PMID
16189514 .
S2CID
4427026 .
Zhang N, Kaur R, Lu X, et al. (2006).
"The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links" . J. Biol. Chem . 280 (49): 40559–67.
doi :
10.1074/jbc.M508453200 .
PMID
16223718 .
Grillari J, Ajuh P, Stadler G, et al. (2005).
"SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly" . Nucleic Acids Res . 33 (21): 6868–83.
doi :
10.1093/nar/gki986 .
PMC
1310963 .
PMID
16332694 .
Voglauer R, Chang MW, Dampier B, et al. (2006). "SNEV overexpression extends the life span of human endothelial cells". Exp. Cell Res . 312 (6): 746–59.
doi :
10.1016/j.yexcr.2005.11.025 .
PMID
16388800 .
Lu X, Legerski RJ (2007).
"The Prp19/Pso4 core complex undergoes ubiquitylation and structural alterations in response to DNA damage" . Biochem. Biophys. Res. Commun . 354 (4): 968–74.
doi :
10.1016/j.bbrc.2007.01.097 .
PMC
1810354 .
PMID
17276391 .
Fortschegger K, Wagner B, Voglauer R, et al. (2007).
"Early embryonic lethality of mice lacking the essential protein SNEV" . Mol. Cell. Biol . 27 (8): 3123–30.
doi :
10.1128/MCB.01188-06 .
PMC
1899945 .
PMID
17283042 .
Ewing RM, Chu P, Elisma F, et al. (2007).
"Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .