From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Pleiotropic regulator 1 is a
protein that in humans is encoded by the PLRG1
gene .
[5]
Interactions
PLRG1 has been shown to
interact with
CDC5L .
[6]
[7]
[8]
[9]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000171566 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000027998 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Entrez Gene: PLRG1 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)" .
^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007).
"Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .
^ Ajuh P, Lamond AI (November 2003).
"Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1" . Nucleic Acids Res . 31 (21): 6104–16.
doi :
10.1093/nar/gkg817 .
PMC
275459 .
PMID
14576297 .
^ Ajuh P, Sleeman J, Chusainow J, Lamond AI (November 2001).
"A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing" . J. Biol. Chem . 276 (45): 42370–81.
doi :
10.1074/jbc.M105453200 .
ISSN
0021-9258 .
PMID
11544257 .
^ Ajuh P, Kuster B, Panov K, Zomerdijk JC, Mann M, Lamond AI (2000).
"Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry" . EMBO J . 19 (23): 6569–81.
doi :
10.1093/emboj/19.23.6569 .
PMC
305846 .
PMID
11101529 .
Further reading
Németh K, Salchert K, Putnoky P, et al. (1998).
"Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis" . Genes Dev . 12 (19): 3059–73.
doi :
10.1101/gad.12.19.3059 .
PMC
317193 .
PMID
9765207 .
Ajuh P, Kuster B, Panov K, et al. (2001).
"Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry" . EMBO J . 19 (23): 6569–81.
doi :
10.1093/emboj/19.23.6569 .
PMC
305846 .
PMID
11101529 .
Ajuh P, Sleeman J, Chusainow J, Lamond AI (2001).
"A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing" . J. Biol. Chem . 276 (45): 42370–81.
doi :
10.1074/jbc.M105453200 .
PMID
11544257 .
Rappsilber J, Ryder U, Lamond AI, Mann M (2002).
"Large-scale proteomic analysis of the human spliceosome" . Genome Res . 12 (8): 1231–45.
doi :
10.1101/gr.473902 .
PMC
186633 .
PMID
12176931 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Ajuh P, Lamond AI (2003).
"Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1" . Nucleic Acids Res . 31 (21): 6104–16.
doi :
10.1093/nar/gkg817 .
PMC
275459 .
PMID
14576297 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature . 433 (7021): 77–83.
Bibcode :
2005Natur.433...77A .
doi :
10.1038/nature03207 .
PMID
15635413 .
S2CID
4344740 .
Ewing RM, Chu P, Elisma F, et al. (2007).
"Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .