The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the
tetraspanin family. Most of these members are
cell-surface proteins that are characterized by the presence of four
hydrophobic domains.
The proteins mediate
signal transduction events that play a role in the regulation of cell development, activation,
growth and
motility. The use of alternate
polyadenylation sites has been found for this gene. Two alternative transcripts encoding different
isoforms have been described.[5]
Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye". J. Cell Sci. 114 (Pt 23): 4143–51.
doi:
10.1242/jcs.114.23.4143.
PMID11739647.