Membrane-spanning 4A genes are members of the
CD20-like family. The MS4A genes are usually organized in a single genomic clusters in mammals, suggestive of
gene duplication events.[1] MS4A genes encode a class of four-transmembrane spanning proteins. MS4A genes have been described to act as a specific kind of
olfactory receptor in the necklace
olfactory sensory neurons in mice (
Mus musculus).[2]
In human (Homo sapiens) the members of this family include: