From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Phosphomevalonate kinase is an enzyme (
EC
2.7.4.2 ) in the
mevalonate pathway
[5]
[6]
[7] that in humans is encoded by the PMVK gene.
Mevalonate pathway
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000163344 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000027952 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Bloch K, Chaykin S, Phillips AH, De Waard A (October 1959).
"Mevalonic acid pyrophosphate and isopentenylpyrophosphate" . The Journal of Biological Chemistry . 234 (10): 2595–604.
doi :
10.1016/S0021-9258(18)69744-3 .
PMID
13801508 .
^ Henning U, Moslein EM, Lynen F (July 1959). "Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase". Archives of Biochemistry and Biophysics . 83 (1): 259–67.
doi :
10.1016/0003-9861(59)90031-1 .
PMID
13662013 .
^ Levy HR, Popjak G (June 1960).
"Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver" . The Biochemical Journal . 75 (3): 417–28.
doi :
10.1042/bj0750417 .
PMC
1204488 .
PMID
14416398 .
External links
Activity Regulation Classification Kinetics Types