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Dipeptidyl-dipeptidase
Identifiers
EC no. 3.4.14.6
CAS no. 91608-92-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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NCBI proteins

Dipeptidyl-dipeptidase ( EC 3.4.14.6, dipeptidyl tetrapeptide hydrolase, dipeptidyl ligase, tetrapeptide dipeptidase) is an enzyme. [1] This enzyme catalyses the following chemical reaction

Preferential release of dipeptides from a tetrapeptide, e.g. Ala-Gly!Ala-Gly. Acts more slowly on Ala-Ala!Ala-Ala and Gly-Gly!Gly-Gly

This thiol-activated peptidase is isolated from cabbage ( Brassica oleracea).

References

  1. ^ Eng FW (1984). "Dipeptidyl tetrapeptide hydrolase, a new enzyme with dipeptidyl ligase activity". Can. J. Biochem. Cell Biol. 62 (6): 516–528. doi: 10.1139/o84-069.

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